ID A0A0L0NG49_TOLOC Unreviewed; 908 AA.
AC A0A0L0NG49;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Eukaryotic translation initiation factor 3 subunit C {ECO:0000313|EMBL:KND92735.1};
DE Flags: Fragment;
GN ORFNames=TOPH_02884 {ECO:0000313|EMBL:KND92735.1};
OS Tolypocladium ophioglossoides (strain CBS 100239) (Elaphocordyceps
OS ophioglossoides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX NCBI_TaxID=1163406 {ECO:0000313|EMBL:KND92735.1, ECO:0000313|Proteomes:UP000036947};
RN [1] {ECO:0000313|EMBL:KND92735.1, ECO:0000313|Proteomes:UP000036947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100239 {ECO:0000313|EMBL:KND92735.1,
RC ECO:0000313|Proteomes:UP000036947};
RX PubMed=26215153; DOI=10.1186/s12864-015-1777-9;
RA Quandt C.A., Bushley K.E., Spatafora J.W.;
RT "The genome of the truffle-parasite Tolypocladium ophioglossoides and the
RT evolution of antifungal peptaibiotics.";
RL BMC Genomics 16:553-553(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND92735.1}.
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DR EMBL; LFRF01000005; KND92735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0NG49; -.
DR STRING; 1163406.A0A0L0NG49; -.
DR OrthoDB; 5482362at2759; -.
DR Proteomes; UP000036947; Unassembled WGS sequence.
DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_03002; eIF3c; 1.
DR InterPro; IPR027516; EIF3C.
DR InterPro; IPR008905; EIF3C_N_dom.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13937; EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED; 1.
DR PANTHER; PTHR13937:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED; 1.
DR Pfam; PF05470; eIF-3c_N; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KND92735.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000036947}.
FT DOMAIN 649..823
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 1..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 846..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KND92735.1"
SQ SEQUENCE 908 AA; 102585 MW; B9B175DC1BA97F6C CRC64;
PTKNHQFSTL APSRSNQPRV PRDHPLRDPG PASQEISPSM SRFFRGGDDS SCDSSSDEEE
LYSGEEEEEK KKIDQDDSDE GSDDDGSEDD SDKESSDDEG GNRQGASKFL KDFESESEES
DEDVRAKVKS AKDKRLDELE ASIKQIENGQ KNGDWTLISA EFDKLSRQVS KLQDGGKTPK
TYIRIISELE DFMNEALAKQ KVTPKKMNAT QARALNAVKQ KIKKSNKEYQ TQVDAYRGDK
DGFMESDEEE EEVAPVPKAK KLPKLEDEAP QDELDDEGFA TVGKGGRTLQ YTPESIFKHL
RTIMESRGKK NTDRLEQIKV MEKLNEIANT PYQQIRVLLT IISARFDLGS GTSNVMPLEH
WKAAEKELST LLTVLETNQD YIVVENVEEW DDDEKPPSLQ AGEKYIKVAG SVVSYVERLD
DELIRSLQSI DPHTSEYIER LQDEGALYNT IFRGLLYYEY LRKEQSLDIP QDSINRIVMR
RLEHVYFKPA QVVKTFEENC WKAVGDKVES IITPRTEDQD AGNLVNVLCN YLFSNSDGII
RARAMLCQVY FLALHGEYYR ARDMMLMSHL QENIPNFDVL SQILYNRTLV QVGLCAFRKG
LVYDAQNTLQ EICGSGRQKE LLAQGVMMQR YNQVSPEQER LEKQRQLPFH MHINLELLEC
VYLTCSMLLE IPLLAQTGSS PDVKKRIISK TYRRMLEYHE RQIFTGPPEN TRDHVMQASK
ALAAGEWKKS TNFIHSIKIW ELMPNCEEIK EMLAKQIQEE GLRTYLFTYA PFYDTLALET
MGGMFELDAT KVGAVVSKMI SHEELAASLD QVTSTVIFRK GVELSRLQSL ALTLSDKASA
LIETNERTLE QRTQGTSNAF ERQGSRGRGG QRGGRGGGRG GPRTGGNPQR QAGGTQFTGG
ALGAAVRG
//
