ID A0A0L0QSP2_VIRPA Unreviewed; 372 AA.
AC A0A0L0QSP2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=AFK71_07730 {ECO:0000313|EMBL:KNE21735.1};
OS Virgibacillus pantothenticus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=1473 {ECO:0000313|EMBL:KNE21735.1, ECO:0000313|Proteomes:UP000036780};
RN [1] {ECO:0000313|Proteomes:UP000036780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26 {ECO:0000313|Proteomes:UP000036780};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Fjat-10053 dsm26.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNE21735.1}.
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DR EMBL; LGTO01000005; KNE21735.1; -; Genomic_DNA.
DR RefSeq; WP_050351169.1; NZ_LGTO01000005.1.
DR AlphaFoldDB; A0A0L0QSP2; -.
DR GeneID; 66872704; -.
DR PATRIC; fig|1473.5.peg.4587; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000036780; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000036780}.
FT DOMAIN 30..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 372 AA; 41762 MW; 949CED6F967F1BF7 CRC64;
MTLKRIKVMT IFGTRPEAIK MAPLVLELNK RTEEFESIVT VTAQHREMLD QVLEIFSIIP
DYDLNIMKKQ QTLAQITTRA LEGLDEVMKK TQPDMVLVHG DTTTTFVASL AAYYNQIAVG
HVEAGLRTWN KYSPYPEEMN RQLTGVIADL HFAPTEKSKQ NLVQENKPLE RIAVTGNTAI
DALKTTVDPS YSSPILERIG EKRLVLMTAH RRENLGNNMQ QMFRAIKRLV ETHADIHVVY
PVHLNPVVKQ AAEEILGNDD RIDLIEPLGV VDFHNFASRA YLILTDSGGV QEEAPSLGVP
VLVLRDTTER PEGIEAGTLK LAGTDEDNIY HLANELLTNK QSYDKMAKAS NPYGDGQASR
RIADSIVDYF HK
//
