ID A0A0L0RZ85_ALLM3 Unreviewed; 1113 AA.
AC A0A0L0RZ85;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=AMAG_01292 {ECO:0000313|EMBL:KNE55396.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE55396.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE55396.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE55396.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GG745329; KNE55396.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0RZ85; -.
DR STRING; 578462.A0A0L0RZ85; -.
DR EnsemblFungi; KNE55396; KNE55396; AMAG_01292.
DR VEuPathDB; FungiDB:AMAG_01292; -.
DR eggNOG; KOG2171; Eukaryota.
DR OMA; VMPRIRH; -.
DR OrthoDB; 22606at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF6; IMPORTIN-4; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054350}.
FT DOMAIN 26..93
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 165..202
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 387..425
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1113 AA; 119373 MW; 43AB5563CF26EC8C CRC64;
MDFATQLYQL LSTTAAATDS ETLRQATTTL NKQFYSNAQC LPALIRIAAE AADAPLRQLA
AVEARKRVDK FWLETPPDVR AQLQQVLVQR VVAEPDTRTA HGLARVISAV ARIEVPAGRW
TELIPLMVQA AGTSPTVAHR EVGIYVLLAL FEVLVDHMQP QLPTLFDLFA KTLADPESRL
VRVTTLEALG EVAEYVGPED KRLIQYLIDL TPQMVTVLRE AIEAGDENGA LRGFNVFDTL
LSSETNVLNA HFAPFVEFLV GTFANTTLAD SIRVMAGNML VLLPLYRRQR LIKLKLSEPV
LTHILPVTTE HDADEDEDED TPGRVALRAI NSFATNLPPQ QVFPFISAKV SAYAQDPHPG
ARRAAMMCVA LILDGCADAM RSHVADLVDL VLHLMQDADV GVRKAACIAL SALADALDGE
VCAQHAKILP VLFALMQDNA HVDVLRNATN ALDAVLDGLG DDILPYIHAL MESLGHMLAV
PDVKVRQVVT AAIGSAAHAS GIEFVTYFPH VYPRIAEIMA IQSEDAEEML LRGIATDTMS
AMADAVGADV FRPYLQQVAA LATESMQLDS PKLKECAYCF FGVLSRSFKA EFTAFLPTLV
PVLFESIKTE ENFFEDDSED LDLSQGSIQI AAGSSSAAAA SGALVAAAAG GDDGFVDMDD
DDEDDDDEDA FKVNSAIAEE KSTAIDVLGD LFEATEAEFL PYLDETMSLL LENTTHYHDA
VRKSIILSLF KILAAMHKMS NPVAWQAGLP APVPLHENVA NMAHVVMSAV LTMFEEEDER
IVAAELCDAL QGALRLVGPA LIQSHGMLDK LANLLLSVLQ GKHLSQMDED GEDMDADELA
EYDGMLIAAA GDVVGALAHV LGGAAFAPYG QRLLPQLNKY FKPSSQTSER SMAVGVLADV
AAGLRDAVTA WHGPMLHVFT RALEDPELEV QSNGCFGLGV LAEFTTTAYD AAALLAPLVP
RVSAPAGAAP LDIPQARDNA CGAVARILLR ADHWRTPAVV ATNALPLLIA SLPLRADYEE
NRPVFDLIGH LLRLGAAGDV DALAQLPAVL APMVAAVAHV LAAEDEVNDE SRAMLGQTLV
ALAASATLRG PVQEAVAALT PEMQQAVQKA MAA
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