ID A0A0L0S2F6_ALLM3 Unreviewed; 1616 AA.
AC A0A0L0S2F6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Polymorphic outer membrane protein {ECO:0000313|EMBL:KNE56728.1};
GN ORFNames=AMAG_02508 {ECO:0000313|EMBL:KNE56728.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE56728.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE56728.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE56728.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG745330; KNE56728.1; -; Genomic_DNA.
DR STRING; 578462.A0A0L0S2F6; -.
DR EnsemblFungi; KNE56728; KNE56728; AMAG_02508.
DR VEuPathDB; FungiDB:AMAG_02508; -.
DR eggNOG; KOG1056; Eukaryota.
DR OrthoDB; 5475408at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR003368; POMP_repeat.
DR NCBIfam; TIGR01376; POMP_repeat; 1.
DR PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054350};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1616
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005547848"
FT TRANSMEM 1029..1053
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1065..1085
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1097..1122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1143..1163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1183..1206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1218..1241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1028..1292
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 1294..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1409..1482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1583..1616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1410..1458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1583..1600
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1616 AA; 170850 MW; A34176A3D4089FA2 CRC64;
MLVALLAMCW MPMLAVAQQA LALNLTLTVD PSLTSSPGQP STTFAKLADA WSYVTTSAAS
VTGPVYAKVL LLNGTHYLTA TNTTVMAPTS DRVTIEHYPV WWTPRLYAYS NGAMFTDARL
ATVQIRPDPA FVPSNANPWV VGRGNVSLSF TGVTLSAFRW TDDSVTSPWA VFDMRDTSQL
SIIYSIVRDA GVANPVFAVT ARGQSRVVVS SSFVAAEGPS VDLVARFNVE FSAQDTAALT
ISNTTFLYLG AWREAIIKST GVAPTVLVSK SYLNMNYELP VFHAYGSVAV YDRVVFRGNT
GVLASGTAGV GMVLYGASLQ AYGCTFSYNN GAQTGTFVFA NAYGYIADSE FIANEPSVIM
VARAAGSTEL TMVRSTISNY TSANRFFQIS ETARVTLDSC VIRDNQAAWI AGSYITSLLR
VWNSTITGNQ FGLSSFYITQ NIHAEFIDNK FIKNYADNYF LVSDRNGTMY MRGNKFIDNT
FGDNGGPVVT FGRNLTMVDT EFTRNAYSWL GAGNRLIQVQ GSVTGTVVNI VRANFTDNNV
GNAIIVNNLA AAVTVESSTF VRGGNALVTK STVGSLRVDT STFENNKPLA DGSVVFAQGP
AWITRSSFVN NVGADAGGAV VWVPQSKNQT LIVDQCAFTG NAAAQDGGAI YMNGGLVANT
AILRNVFSKN LAKRGGAIYA TDGTEPITGV ASNTFIGNSA LSGQGPDVAS QPMTLQVASG
PVGQGSKFVP PNAQTYSGDT IGAFSVVAID AYAQSVATTV DETFLLQVVA VPVDANATSP
SDVTLAGEVS KAILDGSTTF KDLQLMGPPG TYQVQVLSQN ERYPASSFNL TDMVTLQPCT
PPRIVTAVNG APVCALPTCS QGCFAGQGTC VAPNVCQCLP DFDGLDCSMR AGYNDAISLL
VRLSGNVTSL RRRAVDPVTA AAEAVAAQVK ALLASTPAVT ALGDPVIRRV TIVDRIANVS
VSVRGPNQSF IEANVLESVV PAVSQQMGAA SSWTIPAVSG TGSALTASWA DVVYQPAPRF
FLDYSHPGVL GALSVACILA VLTLFVMGVL TVYRSTPVVR ASSYMFCMLI CMGLLVGYAV
VPLTAGQPTV ATCTAQIWTL LLSVVLVLGN LITKTLRISF IFGARKRGRV GGLSDLAMAR
YSLALFTGQV ILLVLWTTLS PPVPSLIEMP TYRYWTCGMR SGAPVFLGLL GAYNVSLIIA
AVVLAIQTRG AQGAFRESTR IAVCVYTMVV VAGAAATVVM LPATPPGLSF GVKAGAIVII
NGFITAQLFL DKVHIAIFRP DLNNMDALNH RATNAAKGVS RAGRGTSSSR SGSRRTGTSS
RARQRVAAHY SKEQQQKHDS WWRRILGAAS KTGTAAQANA SVASASATGA SSGNLTAGSM
GNSIAALTQG GRRGGPGAAA AGNRRTVSIA GPAGASNNTI SSQGNLLGSS GGRNRHGSND
PEDQSGTLPA TSMSGPLPNG KVSAVPEANE EQLEEQVPAL GPDPVRDVFQ VRKGSRGFLR
AQYRTMYVHL FPLTEHVVVS RSPQPVEADV IPLAHCRLRI LPGNCLKLSI AHHQMWWLRT
RHDDVFQQWA AWLTDLCTPR EFFDEDEDDP DGEGFEDDED WGGSASFGGS MQLGPS
//
