ID A0A0L0SWV0_ALLM3 Unreviewed; 818 AA.
AC A0A0L0SWV0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=STE/STE20/FRAY protein kinase {ECO:0000313|EMBL:KNE66885.1};
GN ORFNames=AMAG_11361 {ECO:0000313|EMBL:KNE66885.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE66885.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE66885.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE66885.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG745351; KNE66885.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0SWV0; -.
DR STRING; 578462.A0A0L0SWV0; -.
DR EnsemblFungi; KNE66885; KNE66885; AMAG_11361.
DR VEuPathDB; FungiDB:AMAG_11361; -.
DR eggNOG; KOG0582; Eukaryota.
DR OrthoDB; 152877at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR047173; STRAD_A/B-like.
DR PANTHER; PTHR48014; SERINE/THREONINE-PROTEIN KINASE FRAY2; 1.
DR PANTHER; PTHR48014:SF24; SERINE_THREONINE-PROTEIN KINASE FRAY2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KNE66885.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000054350};
KW Transferase {ECO:0000313|EMBL:KNE66885.1}.
FT DOMAIN 199..449
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 776..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 740..774
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 228
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 818 AA; 84741 MW; D2C383417AC3D23A CRC64;
MATSATTPAS NMPSATPATD SAPSDLGHAR PAAAPVTGDA TALPVLGALA PATDRLNAGS
TSALGSELQS SAPAPVKGAP AAAAAPPPPA PAVNPSTMTP LAFAPANYHT PTPAPAAPLV
SLPSVASASF PRMAQVAPQR TNSSSSGWKR TLALGGAPGH LLSSTASMMS GSSMASSASN
AACADPNEGV FFSSNSSDYT IETAIGYGSS ASVYSAIYRP VQRRVALKVI ELDMFERNQI
EELRRETQVM SLCKHPNVLR VYTSFVADSR LFIVTPYLSA GSVFDIMRTA FPEGIDEISI
ATILKQVLQG LEYLHRNGHI HRDVKAGNIL LDHDGTAILA DFGVTASIEA ADRKARARRR
HLVAGHHVSR DGHGHAPLAK VPPVKVMMLT LTNDPPTLDR DATRTTEKLL SHPFLKCAKK
RSSLVQSLLQ DLPPLPERAR KRAGNVPVLP ISNAAESARD RDGGTRGQSH ISWDFDIREQ
SPVPEHDPSV LGSLNAAAAP LAIDQIQGTA PGVGLGIDAM PKVEVRKGRF SVSENVGSIE
PGAAASAAYP AAGVPNTGTS TPVSASTVGT PLTATGATEP VLQRKGRFEV SINADPTMVL
AGESAVSPQL PMHAPAYSQS SRGSSRRGGG GGGGMGGADM HPASHLTGGS SSGGSPAVYT
LAPSSIDTLV RRQDEMMRMM LVIMERVQFP HPHSSATSDP AHSFPLPPWL ALAHAPFQPA
PAPSLPEPDA SASTGLASTM ALLTRQLQVV LAENEQLRHR VHDLRQEVEQ LRATNNIHST
GPELALHGVG SNGDPPAAAA ASSLADQPGG GVGLPLLL
//
