ID A0A0L0T1T3_ALLM3 Unreviewed; 1768 AA.
AC A0A0L0T1T3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=AMAG_19754 {ECO:0000313|EMBL:KNE68585.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE68585.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE68585.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE68585.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG745357; KNE68585.1; -; Genomic_DNA.
DR STRING; 578462.A0A0L0T1T3; -.
DR EnsemblFungi; KNE68585; KNE68585; AMAG_19754.
DR VEuPathDB; FungiDB:AMAG_19754; -.
DR eggNOG; KOG1808; Eukaryota.
DR OMA; HIGEGPW; -.
DR OrthoDB; 37271at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039891; VWA8.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07728; AAA_5; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054350}.
FT DOMAIN 1578..1759
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1400..1439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1455..1474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1455..1471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1768 AA; 193752 MW; F0F7A1E58176ECFD CRC64;
MADKKGSSPT TTDGQRKALI RIGDIASQIA VPTHQHLVPY VDPEELALTK RTRQVLRWLL
QKEKLNQDAF LLGPPDGRMR SIAFKFAQLT NREVEYVAIS RDSTESDLKQ RREIEGGTAK
YVDQCCVRAA IHGRILILDG VQSCERNLLP LINNLLENRE MALEDGRFLV SPKRYQALLN
DSSADAAALA DRKLVPVNPK FFVIAIGLPV PPFTGYPLDP PFRSRFQAKF VPRLNADETV
RTLTTSGSTK LGPAHVDALK RIATVAEVLA ANQAEYRLAD FTGDLAVIAK LLHHGVAPIH
ALDLVYPFMS LPTTDKHSRM VLEGVLRRFG LTHEQLTDVP MPDLMPALRD PSFPTGLALT
PTFEAALMKM HACHTAVGDF CLVGGKGAGK SHLVRHFCAS LGLEMLLVPV FKDMSSRELL
QRRSTTFAGD TTWVDAPLVD AMLTGRVAVL DGVESLAHGS LATLECIVHN RSVTLPDGRR
LVSDKQYARL PAREKALVER IHPSFRLIAL ARPSVMGSDA KTWLTPEAAA LFPFVQLAPL
AKAEEAALLQ ATVPNADPAL VDQLIQVAVA LQNAHDDVGA LAHSVSLRQL IKLAQRMTAF
PGDSLWDEVH RVTMTRFAPG MVREQLSGLM AQVGVAMPPP RRADEEAPLS LRKVENGQKL
AIGDVVVPIK QDADPLLIPH TLFYENQRQF TVLRDLLKDW LLGEHILLIG NQGVGKNKLV
DYLLGQLQRE RQYIQLHRDT TVQALTAIPV IKEGVLSYED SPLVVAARMG HVLVVDEADK
APTHVTAILK SLIEDREMLL GDGRRITTMP QSNLDVVLHP DFRMIVLANR PGFPFLGNDF
FRECGDVFAS HAIDNPDVPS EVAMLQQYSP NVAVSLLEKL SRAFAELRVN AQDGDINYPY
STREIVHIAR HLEQFPDEGL ANVLHNVFDF DAMDSTTREV VIAALKKHGI PIATQDGYQI
QLAVMHPLPA PAVQHEWVAA GPTVEARVER KPPALRGGWD LKLSPAQTLT KLEGRNNVFS
EKLFSVHLPM ETTVLSVAAF DHVVYLVATN PIQLIVLDTQ AWSVATVSLH EYFPLQRGFP
ALHVVAVARD QLIVVNVDDG TVLVVKEWKI FSMSVTLIKG RATMVRRVAA GAAGAPFVAV
VAQEGESHVD VVTVDGDHAR VALPSPVARM HAATGPRILV QSPASALLLM DVATARVQEF
APTSSDVAMP LAAMHALDDA RFLGVASVDQ VLVLDMQPAR IAAHRVATLE NPYVNVDPVA
RALLVQQHVV VYPSAVPGQG IAEVLDLGHR ATRHVPVELP LPFTAKLQTE ATVAEYKGDR
VPAALAVLDV GAGCVAVVDS TGMIQVLQVT LEQLKTDLHD WRRLIGSDAS ADRERLDVTI
VDDSADDESI AKQLEALGIG KGKGKGSGEG EGTGDGEGKG SGSGTGVSGE GGSTGATRTS
AEALSLEEII TNAKGDSQAT ASVTIRTSAP ATGEITEAIR EMHDEAVRQR MAQLEMREPD
MKTYQTYKEE VAKEIQQVRQ LIESTQRKQK ERVWLKNQST GELDDRKLVE GLVGDTNIYK
RRGDEDPTMG SLFDVPKRVI FSFDLSASMF KFNSHDARLQ RSIELALLVM QSFRGFENKF
RYEIRGHSGD SASLEFVTES NYPKNEKEEL RVLTKMSSHA QYCLTGDHTM ASIKQAIQDV
TKQELDEAFV VVLSDANISQ YNIQPNDLAQ VLSSDDRVQA YIIFIGTLAD QAEQLRKAMP
GKAFSCLDTR QLPHIMKRIF TGMVRSNL
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