ID A0A0L0T870_ALLM3 Unreviewed; 498 AA.
AC A0A0L0T870;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DEAD-box helicase OB fold domain-containing protein {ECO:0000259|Pfam:PF07717};
GN ORFNames=AMAG_20264 {ECO:0000313|EMBL:KNE70947.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE70947.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE70947.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE70947.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the INSIG family.
CC {ECO:0000256|ARBA:ARBA00007475}.
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DR EMBL; GG745369; KNE70947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0T870; -.
DR STRING; 578462.A0A0L0T870; -.
DR EnsemblFungi; KNE70947; KNE70947; AMAG_20264.
DR VEuPathDB; FungiDB:AMAG_20264; -.
DR eggNOG; KOG0922; Eukaryota.
DR eggNOG; KOG4363; Eukaryota.
DR OrthoDB; 2782284at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR025929; INSIG_fam.
DR PANTHER; PTHR15301; INSULIN-INDUCED GENE 1; 1.
DR PANTHER; PTHR15301:SF3; PROTEIN NSG1-RELATED; 1.
DR Pfam; PF07281; INSIG; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054350};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..89
FT /note="DEAD-box helicase OB fold"
FT /evidence="ECO:0000259|Pfam:PF07717"
FT REGION 163..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 318..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 51460 MW; 095CFE633A8AB7AA CRC64;
MTTRTCATNS VNICFLRGYF SQVAFSQPDG RYLTAAGRHA VYIHPSSVLF GKRVPVVAFV
DLVGSESGRW FIRGVSRVDP AWVAEAAQAV VQEAKDEAAK ARKGKAPKPR PNAVHAVARA
TIDRPWLVPT SLFLLGYALS LLVVNLHTQH HVTHYDRLGT AGSNARIAGV PPPPPLPPPP
SGTILGRPPR FAHSWLPLVG AVSAVIVGVA YLIADACAGD LGRRPPSAAA TAGLLSRRGS
VSEAAGRFLV VSLSSTSLAS LVAPAPRTDT CPLPPRWGSS SSAAPSRTAS STGVRCGAGG
GGGPRMVLLD DADVADPDDV DDELLGPRSA VDAAPGSMSP PAVGATASAA EGDPPRTSAT
ARLRYRSKRG LILRCLGGVV GINYAVSKVP AHPYLLSAAL LALALAVYSM VDRTRRGFFV
SLFVAAVGTL VCHSLTLAGY LAFVQPDLLG TIKAWVPVLI FTTAVGVGSA ARVLLVIASR
PAVTSGGVGA VATPQWSL
//
