ID A0A0L0TDK9_ALLM3 Unreviewed; 1416 AA.
AC A0A0L0TDK9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMAG_16423 {ECO:0000313|EMBL:KNE72664.1};
OS Allomyces macrogynus (strain ATCC 38327) (Allomyces javanicus var.
OS macrogynus).
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Blastocladiaceae; Allomyces.
OX NCBI_TaxID=578462 {ECO:0000313|EMBL:KNE72664.1, ECO:0000313|Proteomes:UP000054350};
RN [1] {ECO:0000313|EMBL:KNE72664.1, ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|EMBL:KNE72664.1,
RC ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Allomyces macrogynus ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38327 {ECO:0000313|Proteomes:UP000054350};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Borenstein D., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Roberts A., Saif S., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Burger G., Gray M.W.,
RA Holland P.W.H., King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I.,
RA Lander E., Nusbaum C.;
RT "The Genome Sequence of Allomyces macrogynus strain ATCC 38327.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG745382; KNE72664.1; -; Genomic_DNA.
DR STRING; 578462.A0A0L0TDK9; -.
DR EnsemblFungi; KNE72664; KNE72664; AMAG_16423.
DR VEuPathDB; FungiDB:AMAG_16423; -.
DR eggNOG; KOG0054; Eukaryota.
DR OMA; APYLMDN; -.
DR OrthoDB; 3295317at2759; -.
DR Proteomes; UP000054350; Unassembled WGS sequence.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IEA:UniProt.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18579; ABC_6TM_ABCC_D1; 1.
DR CDD; cd18580; ABC_6TM_ABCC_D2; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR044746; ABCC_6TM_D1.
DR InterPro; IPR044726; ABCC_6TM_D2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054350};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1416
FT /note="P-loop containing nucleoside triphosphate hydrolase
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005548749"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 859..885
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 897..916
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 983..1015
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1085..1107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 245..484
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 555..781
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 863..1142
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1179..1411
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 787..839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..839
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1416 AA; 155354 MW; CAC5E61D0C631BE0 CRC64;
MSLLAFAILA NRLWFLNARP DLPAEMTGGG RWLLVFKMIM AVANLAVVIV TLVVEATQPR
PAAASTLFGW ISLCLPLAVA IFSHHLEHHR SRRASSSLSS LYLLTVVVLA VRLRTLALHR
DDYTSTLTTL AGTQLGISAV LFIAENFSSK RMRTDARDGR KQADESPELT ASFLSKITFW
WVLPLLSRAS KTVLTATDLW DLPHLWSSRP NQQRLQHAWE TELKKSGDKA SFARALAAAF
GPRIAVMLLF ALLNTLIVLL TPKFVEYFVG FVVARGTLAE RPLSEGLAMV LVFIAYGITQ
SVLNGQQRHI MQTEMARMLA AIRGVVYHKI MAIPSHDQSQ SGTSGNIVNH CQVDASRIVA
AIQFVAAIAT VPFGLVLGMA LMYQQVGWAM MMVLVVTALL MALMSRIGGP MAKVQTESLK
HNDTRIKLCS DALTGIKTYK LYGWTKPIAD RILAVRDAQL RALRKMTILL SIQAGSTDIM
PTLSAYGSAD LTVQKVFVVT TLYRLISGPM ETLAFGWAPL LAAWVSVQRI TKFLNTPELA
TYVDRSTDTT DPVAISVKDA QFAFVDDKPV LAIDQLEFAR GSVTAVVGRV GAGKTALLNA
ILGEVYQTSP NGSVTVRGTV AYASQKAWIL NASLCENILF GLPYDEKKYR KIIEACALKR
DLAMLVNGDQ TLIGDKGINL SGGQRARLNC ARALYADADL FLLDDPLSAV DAHVDRHLFD
AWFNLDSGLL RGKTVVLVTH AVHHLPDVDR IVAVQDGKIA EVGTYAELMA REDGVVADLV
REYMAKRRDD DEEETSGSAT DDVRNEEKKK KRALEKTLSS TTVASAKDDD KEVESSEESK
ESGSVGWNVY MTYMRACGWV NVFAALLFAC IANAMIIFET IWLGMWGQAA TEGHADFGFY
IGIYGVISVV FAIGILGSLY TTLAVAAFHA SIGMFTKVLH SVMRAPGWFF DVTPAGRILN
RMASDQDKVD LQVPLNLMQF TFLLIYVIAV FINVIIASPW FALIVLPIGV LFVWIERLYL
NVSREVQRLF QISLSPVFQH VTETLDGLPV IRGGYHHANR FEHMALDKID HSGQAWYASI
CTTRWLYVQV ELVGNLIMGL VALLAVLVKD ANAALMGSAL SQAFVLVSIF SEIMTTYGNV
ENTLVSVERI NEYMHLPAEA PEETTAVALD AKWPADGAIE IDDYSTTYRE GLDPVLKHVS
VHVRAGERIG IVGRTGAGKS SLTLALFRII EATSGRITID GLDIAQLGLQ DLRTRLTILP
QDPIIFHASV RDNLDPTGAN DDAAVWRALD SAGLADFIRE LEGQLDAPLT AASMSVGQSQ
LLCLARALLR KTKILVLDEA TASVDPQTDE IVQKTIRREF AGCTILTIAH RVATVMDYDK
ILTLDHGKVV EFDSPEALLA DQESVFYSLA KESKLI
//
