ID A0A0L0UTF6_9BASI Unreviewed; 2112 AA.
AC A0A0L0UTF6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=PSTG_16223 {ECO:0000313|EMBL:KNE90352.1};
OS Puccinia striiformis f. sp. tritici PST-78.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=1165861 {ECO:0000313|EMBL:KNE90352.1, ECO:0000313|Proteomes:UP000054564};
RN [1] {ECO:0000313|Proteomes:UP000054564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race PST-78 {ECO:0000313|Proteomes:UP000054564};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Hulbert S., Chen X., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Puccinia striiformis f. sp. tritici PST-78.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the CLASP family.
CC {ECO:0000256|ARBA:ARBA00009549}.
CC -!- SIMILARITY: Belongs to the TOG/XMAP215 family.
CC {ECO:0000256|ARBA:ARBA00025722}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNE90352.1}.
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DR EMBL; AJIL01000262; KNE90352.1; -; Genomic_DNA.
DR STRING; 1165861.A0A0L0UTF6; -.
DR OrthoDB; 5477703at2759; -.
DR Proteomes; UP000054564; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0061863; F:microtubule plus end polymerase; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IEA:InterPro.
DR GO; GO:0046785; P:microtubule polymerization; IEA:InterPro.
DR GO; GO:0007051; P:spindle organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 5.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR045110; XMAP215.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR12609:SF0; CYTOSKELETON-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR12609; MICROTUBULE ASSOCIATED PROTEIN XMAP215; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 3.
DR SMART; SM01349; TOG; 5.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000054564};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..239
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 297..531
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 612..844
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 879..1112
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 973..1011
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 1223..1482
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 234..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1119..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1472..1609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1895..1967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2032..2083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..295
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1121..1148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1567..1609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1895..1916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1917..1935
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1939..1967
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2044..2083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2112 AA; 228073 MW; A11B8003A6866AB6 CRC64;
MAEPPADSDW QNLSVQDQLY HKLWKARLAA YETLIKQFQL AEDEDDEVFS DWNRDQQWPQ
KAVTDSNAVA QEKGILLVSI YIRLAGRAGS RCRPDCITPL VEKSLATNAR KGTREAATEC
LLGWAMSEAD GDKGEGIVSP VLEGLKSKQP KVVAGAVAAL NALISAFGVR VINIKPILKT
LPQMFAHADK GVREEGRLLV QTIYQFLGAA LDPSLSGLKP VQVKELQDSF ATLDAEGKGK
GTGVPTRETA GQTRDRLQRE AQAALKESTS QNDPAGDDPA EEPEVVDEPP EDIDPYDLAD
PVAILDQLPS GFYEHLASSK WKERKEEALD PLLATLKPAI KIKNDHYDEL VKSLAGRMAD
ANILCVIGAA NCLECLAKGL RSEFAKYRTL MVVPILEKFK EKKVNVVEAL SNCLDAMAVT
VTLSDLNEDI VNFSKHKNPA VKEQTMKFLV RCLRNTIHAI PKAELKSLSD VMLSGLEDAV
VPVREVAAEG LGTLMKLVGK ATFTPIIQGQ DNLRKVKVEE YFEKAEVKYQ PPKAKPKVQA
AKPAAKAPAK KTVAKPAPRA NSPAPTPADN GLGSSVSAKP PPVRPAKKSG GMASAAAGGS
GSTKATEEVR YKMSQEDAEA KAPDCLPASF IEGVGNSVWK TRLAALEELL SWIPEQADEI
EAEVVVRYLN KKPGPKESNF QVWQRVFSVI SLLAEQCPSF SKACMALTIP TCFEKYGDGK
IKEAAGNALI AFAEKTSLGF VLSQAFDSIS KQKAVKIQAE SYLSIDSALI EFGISGVPVR
NLIECLKAGL KSVNAAVRTN ATKALVTAKL GIGADISNFL QDLNPQLLTT TESEFAKTDG
ERPPTPTGQS ADVAQASKGE ASGAKGKRKS GASGDPLDEL FPRVDLDKLV SSGTIRACDD
SVWKTRKEAL TTIQDILEQN KRLKPNLGSP DLSASLKLRL ADANKAVQTL ALDVVSRLAT
GMGKPFERHA RPLAPAILNI LADKNATARN NALDTLTVVA DSCGLDCLAS SVGTCLEIAK
PELRSSALAW FVERVADPAV VKGLDLSTFA SPIISCLEDR NGDVRKGATA LLPTIVQSVG
INSLLEEANN LKPASRNNVI PMIESCRPAA PVKVAASKAP LNKTVSKTAP AANKQQPRPP
SVASVHRATT PSRDERPSLS KSRLGARKPA GTLNSKLASV APPPASPSPA PAAAEVPFRS
GDPKLKTARA SKETGPLKWI IEGAVRKDQI EQLYLQMAPH ISPELLGQLF SKDHHCEKDF
LAGLNVIENW TSDPSIAAEQ VDMEESDVRD RLLANSDLVF KYLTIRLHDT NTTITMKCLD
IIDQYVAVLQ LDGYRLTDYE ASILLPSLIG RCGDSKEVLR TRIRAIFKNL CGIYPFSKVF
QSLIDHGLKA KNARVRSECA EELSALFQRH GLNVCQPAKA LPLIAALISD RDSAVRNGAL
SALASAYASA GDVILKYVKN LSGKEQDMLT ERLKRTEAPV SPKQDRLPTA TEKSASPTPR
GPAAARRTTK PSVLRRPSGA FIPPGEPETN GHPKEGLRKP TLMKSTSSAI PPPTKIHPPA
GARQLASADL SRNNSTSSNN ISNSKIDPRL SLRPSLAQSQ SRGITRAAST DSVVTNTVNY
PGVIGEILSS DDIRSTDALK SIQADIAERP DTLISTADSI VDVISTQMKI AFEHLDGTTP
PMKLRLCKHL MQTLSTLFDR SQLATAVSKE SLVGILAQLT QRLQETADNT SSEHITSLSK
VLNMVLIRIF HNADRSACFG ALFTVLRMTT IDMREIEDEA ELGHRAKYAE LVMKCLWKVS
KTAKESLEDG TLDVSILLRD IDEFLVSIPP AEWRRRANDN VPLADMPLRT VKTILQQVVT
IYGDAVYDAV SVLKNPQDTF VYQYLFRLLN NSWSAGGENP PSSRSIGGSR PMGPSSSAGP
RSPPPSFPIP RPPETGRPRR NSRSSVTSYA STSFSKPGPA TESSSEVELN NHLTEIFAKI
GSPIDSKKGI SDLYQLLKMH PEANSKVDKW ISATGTYFQA YLRRALNNLK ADDPDLPNGG
GTEGLMPSVS TSRPTSANIP ASPSMSTFGS DNGAAANRIS RSHSQDVDLT RLQSLFGFEA
TTTSPTRPHQ LE
//
