ID A0A0L0UTP1_9BASI Unreviewed; 1467 AA.
AC A0A0L0UTP1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=PSTG_16466 {ECO:0000313|EMBL:KNE90089.1};
OS Puccinia striiformis f. sp. tritici PST-78.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=1165861 {ECO:0000313|EMBL:KNE90089.1, ECO:0000313|Proteomes:UP000054564};
RN [1] {ECO:0000313|Proteomes:UP000054564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race PST-78 {ECO:0000313|Proteomes:UP000054564};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Hulbert S., Chen X., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Puccinia striiformis f. sp. tritici PST-78.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNE90089.1}.
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DR EMBL; AJIL01000277; KNE90089.1; -; Genomic_DNA.
DR STRING; 1165861.A0A0L0UTP1; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000054564; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054564}.
FT DOMAIN 164..336
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 386..581
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1091..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1031
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1423..1438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1467 AA; 164208 MW; 6B6C847502D1F952 CRC64;
MDDRYGYRAD YPLFKLPSPL SSQSDYFDEG LDDGSLNDLV DTVDRNHKYP SNQYQELPSQ
GNDQQFTSSP DRDYIPAPQA RRNSSNRIHS TEFQDRYDSP CIYPDDTIMD EDYQESYDLP
VGYHNRQISD EPFPNLIPVT DLPAPHRVLF EFTHFNSVQS ECFPTVYRTN HNVLTNAPTG
SGKTVLFELA ILRMLEYNQS SKAVYMAPTK SLCAERFQDW SRRFDPLGIT CVELTGDSEN
AGLADAKLAN LIITTPEKWD SMTRRWFEFT KLLNNLRLVC IDEVHMLNEE RGSVLEVIVA
RMKTLGTNIR LIALSATVPN ISDVAEWLGD GGVADQNQKA LPGQAPAKTF IFGEEHRPVK
LSKFVYGYSR RPEHTEYQFM SLLNYKLMDH IVTHSSKRPT LVFCGTRKSS LQAAEALSKA
YQKMSTQGDD LPWEAPRSAG TFSDKKLTEL GSQGIGIHHA GLDHSDRRQV ESLFASNQIS
VLCTTSTLAV GVNLPARCVI IRGTKTYRGG AAGRDGFEDY SELDLIQMMG RAGRPQFDDE
GVAVVMTSQN DKMRIEKLVK SETMLESCLH LNLTEHINSE IYMGTITSRS SAIAWLENSF
LAVRIKKNAK HYSISDDQIA PDKQLANFAE AALDLLAQDG LIEEDEDHLI RPTELGEIMS
KFCLRHKTFL GLARMKSSAT MRNLLEIVSG ADEYSTLRLR TGEGVAYKTL NSHPELKCSI
PGKVTQTWQK VMLLIQAVLG GIPLAEVKVE NTNPVMEVNI IWQHLPRICK CLVSLAIARH
DSAVKNCLEL LRSVTAKAWD DSPWVMRQLD QIGEKSVKRL VDSGISTIDK LQNTSNHRIE
LILDRNPPFG TRIVRQARSM PKFYCTMEKI SEAVVPEGVH VCVGITVGLS DTGEPPVWKW
KNYMLMATVL VMTNDQEWIE FRTIQVKLLR ETKQFDIECI LVKPSQTIVT HVACTQLAGI
GTSTRWKPHT LREHYPKPKT ITDDEAASLE VLEGLDTKDL AMSSGGSECE VLGKQSKPKA
TSSNQSLCQE RKTAKVPKLH PKNNNLTHIG AAENKRPDSG AGERLKNGRF RCAHRCKGAC
SHICCRDGVT KPPKIREPKK TSSANSTNPQ NSRLPNSLPV NPIRTTNITR TAEDWRRIRE
AVPGSSTKSN QPKLSGRIRP IKKVVAARRF DSDDNLPSLE ELEEISIGES EEKQPEHKDK
TQIVSPDAEN SLQNRPCEKL TLPEESNLVP KAARRPTGPT SMEKFRNMKK IVEDFDERGI
FRQRKDVSSP PCVAPPTIAE DELPQQKGSP TPSPSPRLNS PTPERNCVDQ QISQVLSDGD
ETDELDEDWD LKIFEGYLAP ASQEGGAIEE STKRRVDQLD ISPSIPTPKK LKPDAGNSLK
PSPDAEEIYP ELGSNMNRKG DGHAQDQREN AEHQPFRQTP STGDKEARPE SDQGSHNDEN
DELDSDDSVM GTIDKVLAWA ESHVVEE
//
