ID   A0A0L1IED8_PLAFA        Unreviewed;       544 AA.
AC   A0A0L1IED8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Methyltransferase type 11 domain-containing protein {ECO:0000259|Pfam:PF08241};
GN   ORFNames=PFMG_04193 {ECO:0000313|EMBL:KNG77979.1};
OS   Plasmodium falciparum IGH-CR14.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG77979.1, ECO:0000313|Proteomes:UP000054562};
RN   [1] {ECO:0000313|Proteomes:UP000054562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA   Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "Annotation of Plasmodium falciparum IGH-CR14.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000054562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA   Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA   Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA   White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT   "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG665424; KNG77979.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L1IED8; -.
DR   EnsemblProtists; KNG77979; KNG77979; PFMG_04193.
DR   Proteomes; UP000054562; Unassembled WGS sequence.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008175; F:tRNA methyltransferase activity; IEA:UniProt.
DR   GO; GO:0043412; P:macromolecule modification; IEA:UniProt.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13069:SF21; ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8; 1.
DR   PANTHER; PTHR13069; UNCHARACTERIZED; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054562}.
FT   DOMAIN          360..431
FT                   /note="Methyltransferase type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08241"
FT   REGION          466..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        468..482
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  64833 MW;  777DA5D1A36C0E16 CRC64;
     MNFIRLSLDS YPVKYYKRTY KVTNILKVNG IGLRKWDCEK IKNFISKFDV TCMIYLIDNE
     DMIYIEFYRK KDCTFVYKFF NDTLPTGSTL STSDVSAEYA NIKYEINNNS CTVYSCDYSC
     LLKHKDYITI INNVLDKNLS DEILENYKNE KWLMYTKNDE INVGYYFCRN IPNKIYKSYC
     ISKLDSFFSL EFLERITKIF NNRQPNQITI LNCHLKKAIE YVIESKEKLN LVIESNTLLR
     IKGKLRHEII FGIPKKKKIQ MQDKLMDRKN SYLVIFRFIR EDNIKNFVTQ KIKNKIPQNE
     RQEKDCVPIN VNEYTSEKLE KMYVLDVYNQ IALHFGHTRY KSWKNVENII NEEKEGNIIL
     DVGCGNGKNL SESSKYFYIG LDFSLYLLML ARKKMNTDLL LANCINIPLR SNLADLCISI
     AVIHHLGTHE KRAYEQQENV VGNRKFDSQD IFVPWYFQQQ YKTEGYDDDA EGEGEEEPEK
     ENEKEKEESH KFKPVKKDLV KLERYYHVFK KEELYELCNS IEEVKVEKFY FDCNNWGIIL
     RKIF
//