ID A0A0L1IEP9_PLAFA Unreviewed; 484 AA.
AC A0A0L1IEP9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Splicing factor {ECO:0000313|EMBL:KNG77633.1};
GN ORFNames=PFMG_03892 {ECO:0000313|EMBL:KNG77633.1};
OS Plasmodium falciparum IGH-CR14.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG77633.1, ECO:0000313|Proteomes:UP000054562};
RN [1] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HTATSF1 family.
CC {ECO:0000256|ARBA:ARBA00007747}.
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DR EMBL; GG665348; KNG77633.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L1IEP9; -.
DR EnsemblProtists; KNG77633; KNG77633; PFMG_03892.
DR Proteomes; UP000054562; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd12281; RRM1_TatSF1_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034393; TatSF1-like.
DR InterPro; IPR034392; TatSF1-like_RRM1.
DR PANTHER; PTHR15608:SF0; HIV TAT-SPECIFIC FACTOR 1; 1.
DR PANTHER; PTHR15608; SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000054562};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 206..292
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 433..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 57393 MW; FC7ED8A0E9A7D183 CRC64;
MNNNENQKNE IITLTKDNTA TTTTSSTTYK NNNNNIIMDE QEQCCYYIYV NNISYGPYLV
DQVIQMLNEK RINSMTLIFK NGDNNWKYLY NDDILKKYIC NNNMLDTSYL ENIKSDQVQN
KINEQNQNDN KTQNNKDVTH KSNLEHSKIN EHDQYTKNHN NHSNQFITNQ EDELERIRKR
EKKKRYLERK KEKIEKGLCD KKIKNSSIYI TGLPNDVVKE EIYEVFKKAG IIKIDTERNE
PQIKIYYDDN NNIKGDALVT YVYTQSVDMA IKYFDNFLFR QNCIIHVEKA QFNNKKKQVI
KISKEEILKK KKKIKAAKLE QLRLQRGGEV YTGTKKKIVV FRNVFSYEDA MKYDEGDSFY
EFIKNMLEME IKKYVPVHKK HPHGIVCVKF KGVEEAETVC FNDIELNGKK LEVYFYDGKQ
DFKSQCLSPK NKEKYDLQNV NSNEDLNEDT KDDKDPQTLF NPNLKSFHEW IDNQSEDEEH
EIMG
//
