ID A0A0L1IMN1_ASPNO Unreviewed; 306 AA.
AC A0A0L1IMN1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KNG80530.1};
GN ORFNames=ANOM_011371 {ECO:0000313|EMBL:KNG80530.1};
OS Aspergillus nomiae NRRL 13137.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1509407 {ECO:0000313|EMBL:KNG80530.1, ECO:0000313|Proteomes:UP000037505};
RN [1] {ECO:0000313|EMBL:KNG80530.1, ECO:0000313|Proteomes:UP000037505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13137 {ECO:0000313|EMBL:KNG80530.1,
RC ECO:0000313|Proteomes:UP000037505};
RA Moore M.G., Shannon B.M., Brian M.M.;
RT "The Genome of the Aflatoxigenic Filamentous Fungus Aspergillus nomius.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNG80530.1}.
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DR EMBL; JNOM01000587; KNG80530.1; -; Genomic_DNA.
DR RefSeq; XP_015401453.1; XM_015556627.1.
DR AlphaFoldDB; A0A0L1IMN1; -.
DR STRING; 1509407.A0A0L1IMN1; -.
DR GeneID; 26813175; -.
DR OrthoDB; 2232005at2759; -.
DR Proteomes; UP000037505; Unassembled WGS sequence.
DR GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:InterPro.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020630; THF_DH/CycHdrlase_cat_dom.
DR PANTHER; PTHR48099; C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED; 1.
DR PANTHER; PTHR48099:SF3; METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]; 1.
DR Pfam; PF00763; THF_DHG_CYH; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037505}.
FT DOMAIN 15..116
FT /note="Tetrahydrofolate dehydrogenase/cyclohydrolase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00763"
SQ SEQUENCE 306 AA; 34312 MW; A11B02A10CE3C05A CRC64;
MAPRIGETVQ PDDLAKRAHR QISEMLRDSS KRLFLMGILA SDDAGSTQYA NWTRKTCQEI
GVHFHLMKLS PENVATYIRA INANNSVHGI IVYYPIFGDQ RDDEIRQFVA PSKDVEGLNH
QTVHRPSDVA EPRPPKQGRS IIPCTPRAVA WILEWMDVHD RTRPAGERLR DEEICIINRS
DVVGLPLAQL LAGEGARVYS VDISGVQLFQ RLYYPWHSEG LHGKDLPNWT LQTAVQRSRV
VISAVPDPAF KVNTKWLQRG AICVNVSSEK NFEPNVVEVA SKFVPRVGSV TIGALLYNLI
LCSARS
//
