ID A0A0L1IQD5_ASPNO Unreviewed; 1119 AA.
AC A0A0L1IQD5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Zn(2)-C6 fungal-type domain-containing protein {ECO:0000259|PROSITE:PS50048};
GN ORFNames=ANOM_010009 {ECO:0000313|EMBL:KNG81413.1};
OS Aspergillus nomiae NRRL 13137.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1509407 {ECO:0000313|EMBL:KNG81413.1, ECO:0000313|Proteomes:UP000037505};
RN [1] {ECO:0000313|EMBL:KNG81413.1, ECO:0000313|Proteomes:UP000037505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13137 {ECO:0000313|EMBL:KNG81413.1,
RC ECO:0000313|Proteomes:UP000037505};
RA Moore M.G., Shannon B.M., Brian M.M.;
RT "The Genome of the Aflatoxigenic Filamentous Fungus Aspergillus nomius.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNG81413.1}.
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DR EMBL; JNOM01000450; KNG81413.1; -; Genomic_DNA.
DR RefSeq; XP_015402336.1; XM_015555265.1.
DR AlphaFoldDB; A0A0L1IQD5; -.
DR STRING; 1509407.A0A0L1IQD5; -.
DR GeneID; 26811813; -.
DR OrthoDB; 2683144at2759; -.
DR Proteomes; UP000037505; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00067; GAL4; 1.
DR CDD; cd17480; MFS_SLC40A1_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR021858; Fun_TF.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR InterPro; IPR001138; Zn2Cys6_DnaBD.
DR PANTHER; PTHR11660; SOLUTE CARRIER FAMILY 40 MEMBER; 1.
DR PANTHER; PTHR11660:SF57; SOLUTE CARRIER FAMILY 40 PROTEIN; 1.
DR Pfam; PF06963; FPN1; 2.
DR Pfam; PF11951; Fungal_trans_2; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037505};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 53..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 499..529
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000259|PROSITE:PS50048"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1119 AA; 125417 MW; 8BD6F050A804D713 CRC64;
MSRGDSTDEA EPFLAPSPSS ESIETPIRAS KPVLVRLYIS HSLSTWNSRM FEFGAVLFLA
SIFPGTLLYA SIYALVRSLS AVLLSSWLGS IVDRSNRLKV IRQSIRSPYI SPLLFAVVTL
LACFEKLAYT ANTVAVERDW AIVVSDALQI PRQDLNASMR RIDLVCKLLA PVVISLIDSF
STRAAIWTTL GVNASCVLVE YFAIAQVYQS VPELERTQET DVNQNGEEAT SEDQIPQRRI
AHSMVQYTRG VVAPWREYVS SPLFLASFAL SLLYLTVLSF GTTMVTYLLH TGFNSLQVSG
MRIGAVIAEL SGTWAAPFIM NKIGPIRSGL WFLNWQFGCL AAAVAAFAFL NNSSQLVAVS
LIVGVALSRI GLWGFDLSVQ FLVQEGVDEH ARARFSSTEM ALQNIFELFS FATTIVFPLP
EQFKYPVYIS YGAIAMAAVC FAAYVRKERG HLLHTSKCFG GDKLRLFGGE VPTRDIRSKE
VQVPKARGTG RSGPRRRTGC LTCRARKVRC DEVKPTCANC TRLRLQCIYK TIVPGIASRR
STQRVPQVPQ QAFTIDPAPA HVPDRLDVNY FDTVLQPREL RPRRASHMLP HQMTDHTLPS
TSVAVPDFPN FDMLSFIGEI TSDFEQKHLD LTNGVSAFTL TSDALSPTTL GNVGGSNYIL
QQPTWTVDTS VGTLPSPSDS QSDGVQNIPS GDTTIWPETR ETYEEQLLSH FVEIDPPPTP
FGSISLEWNY VRSVIVSLSA DASYLLNALY CYSDIRKSME EGKRWRAAPV YHRQASSEIQ
SCITESMDDS LLKRALTAVF LLMLSEVVSF PELGDSNTSF LHSAYFLLQR FHHRTKSWTG
FGHLIVSWIS LLDVRALIAG RDGDPLVELG MLDQVDTAET GQRSEDELLS KPGYLIHNAI
VGPAYSFLFK AQQVIRRIVC LDMHHRRRGT VSDEFEVLQI AHQIGADLEA LWNKRPRVLD
IYDKPEELYD TLQPAVADEV CRTFRQYMAN FLAIFIYLHR VAFVIYPRTD RVHRAVDQII
QLATVESGSV NHRLPISFTW PLFVAGLEGS LEQRGWIIQE MQRMADLPSD HRPVAQRHPN
AKKILLLLEE MTKRQDASRT WADSRLVRRE LFVDPFVLI
//
