ID   A0A0L1J095_ASPNO        Unreviewed;      1032 AA.
AC   A0A0L1J095;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   22-FEB-2023, entry version 19.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   ORFNames=ANOM_006051 {ECO:0000313|EMBL:KNG85167.1};
OS   Aspergillus nomiae NRRL 13137.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1509407 {ECO:0000313|EMBL:KNG85167.1, ECO:0000313|Proteomes:UP000037505};
RN   [1] {ECO:0000313|EMBL:KNG85167.1, ECO:0000313|Proteomes:UP000037505}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 13137 {ECO:0000313|EMBL:KNG85167.1,
RC   ECO:0000313|Proteomes:UP000037505};
RA   Moore M.G., Shannon B.M., Brian M.M.;
RT   "The Genome of the Aflatoxigenic Filamentous Fungus Aspergillus nomius.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|ARBA:ARBA00009340, ECO:0000256|RuleBase:RU367072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KNG85167.1}.
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DR   EMBL; JNOM01000170; KNG85167.1; -; Genomic_DNA.
DR   RefSeq; XP_015406090.1; XM_015551308.1.
DR   AlphaFoldDB; A0A0L1J095; -.
DR   STRING; 1509407.A0A0L1J095; -.
DR   GeneID; 26807855; -.
DR   OrthoDB; 38995at2759; -.
DR   Proteomes; UP000037505; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR024687; MMS19_C.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF12460; MMS19_C; 2.
DR   Pfam; PF14500; MMS19_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367072};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037505};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          40..297
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
FT   DOMAIN          545..900
FT                   /note="MMS19 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12460"
FT   DOMAIN          901..968
FT                   /note="MMS19 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12460"
SQ   SEQUENCE   1032 AA;  114022 MW;  76F8CD6C5EB9E01F CRC64;
     MSALQTFLLV VDHDKEEAKQ IAERIAQDVE TKKTTLIEVV QSLGEYINDE DPILRGKAVS
     YLTAVIKSLP PKFLSRQQIQ VLTTFFCDRI EDGGAVAGLD TLQKLDRFNK ALAEDVAQAI
     FERFQDLQSR SQSQRFQVYQ LLNELMVKHR SALHDMGEHS LVGIVDLMTG EKDPRNLMLV
     FSILKVVMME WDISNHAELL FDSVYNYFPI TFRPPPNDPY GITAQDLKDR LQECISSTSL
     FAPHSIPSLL DKLDSTSPNV KKDALNALIA CINSYDPDTV SRYSITIWDA LKFEVLNAQE
     ELLSELSLQA LQDIAKRLSE GVTQVSDLLP LAQYMRPITR ECNDQLREPQ QKQAKPAQQI
     LGFISAASFA SFMLAVQAVV APLLTVYQEA DGIAKQRALL DTLVVLFDSA IKIFGEWATR
     TPETNAENPL LEFKDQFSDI FGQALMGVIK EEVSFRVSAL KGLLRLSTMR NFFQDNEVGL
     FVQYLDEILL KEESIGRDDL KKEAIAALTE ISKHKPRLIM DITFPAFVAT LPDFDDGTNS
     NYLPTLESLA QISVEKDIFE TLVRRLLSKL NILLQKEQPG SVAYPRAILI TILYVMSQRN
     MDQDPNLELY YDKIVVSLCR HAAVSASGKA NNNVLNDATV LDTLGRLCNL IVRALPRNKQ
     DEVAESVYTL YSSADDFSPV PFSQSASDDQ QRTMIISTYL LAGLPTDCAN LPYTSPNMSA
     LLFDVVKRST TECVPATHLA LLRHLALLVN KFLPKSELSL AAELFDTILP ASAEGKKLSP
     EPIKTLFWLS KALILRLAPK TTDLLTSLLS LLSSQDEVTS TTAARSFAIL LRDDDVLSAT
     NGANIRLLSK QRVFTTLVPL ISSKIREVNV AGSDSPTPGH IKPAHLTALS GILSTIPPSL
     SVRTATLETL AVIIRDSGVG VIEECGHIQS LVTRLLKTAE HKPASDKAAA VNSPRLRVDA
     LKCLFLLAQT PASDAPAVAK VGKLSPLLPV KAQVVRALGF VLDDPKRDVR KAAVDARGAW
     LRGVDDAPDD DE
//