ID A0A0L6CXB1_9RHOB Unreviewed; 387 AA.
AC A0A0L6CXB1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Ribosomal RNA small subunit methyltransferase B {ECO:0000313|EMBL:KNX42417.1};
DE EC=2.1.1.176 {ECO:0000313|EMBL:KNX42417.1};
GN Name=rsmB_1 {ECO:0000313|EMBL:KNX42417.1};
GN ORFNames=ROTO_09260 {ECO:0000313|EMBL:KNX42417.1};
OS Roseovarius tolerans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=74031 {ECO:0000313|EMBL:KNX42417.1, ECO:0000313|Proteomes:UP000037046};
RN [1] {ECO:0000313|Proteomes:UP000037046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EL-164 {ECO:0000313|Proteomes:UP000037046};
RA Voget S., Bruns H., Wagner-Doebler I., Schulz S., Daniel R.;
RT "Draft Genome Sequence of Roseovarius tolerans EL-164, a producer of N-
RT Acylated Alanine Methyl Esters (NAMEs).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNX42417.1}.
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DR EMBL; LGVV01000008; KNX42417.1; -; Genomic_DNA.
DR RefSeq; WP_050661861.1; NZ_LGVV01000008.1.
DR AlphaFoldDB; A0A0L6CXB1; -.
DR STRING; 74031.SAMN04488077_10276; -.
DR PATRIC; fig|74031.6.peg.948; -.
DR OrthoDB; 9810297at2; -.
DR Proteomes; UP000037046; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000037046};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 135..387
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 341
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 248
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 288
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 387 AA; 41178 MW; E299D4BC592E1374 CRC64;
MTPGARVAAA ISVLDAVRAG EAAEKALTGW ARGARYAGSK DRAAVRDHVF DVLRRWRSCA
ALGGGDDGRH LMIGAMRSEG IDPHTVFTGD GHAPTALTEP ERAGGHVPVG LDALDLPDWL
WPHFETSLGA SAEGAAEMLR HRAPVMLRVN LRRGTVADAQ AQLASEGIDT TTADIAKSAL
QAISGERKIA GSVAYAEGLV ELQDGSSQAA MEALQITKGA RVLDYCAGGG GKVLALAARA
DAAWYAHDIA PQRMNDLPAR AKRAGVEVTR LETGAIARAE PFDLVLCDAP CSGSGTWRRS
PEAKWRLTPE RLEDLTQIQY EILARTAPRV SDGGCLAYAT CSVFKQENEA VVARFLQEHP
SWRLGQQRTW PISGAGDGFC LAQLVRG
//
