ID A0A0L6JRM9_9FIRM Unreviewed; 318 AA.
AC A0A0L6JRM9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
DE Flags: Precursor;
GN ORFNames=Bccel_3693 {ECO:0000313|EMBL:KNY28419.1};
OS Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Pseudobacteroides.
OX NCBI_TaxID=398512 {ECO:0000313|EMBL:KNY28419.1, ECO:0000313|Proteomes:UP000036923};
RN [1] {ECO:0000313|Proteomes:UP000036923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2933 {ECO:0000313|Proteomes:UP000036923};
RA Dassa B., Utturkar S.M., Klingeman D.M., Hurt R.A., Keller M., Xu J.,
RA Reddy Y.H.K., Borovok I., Grinberg I.R., Lamed R., Zhivin O., Bayer E.A.,
RA Brown S.D.;
RT "Near-Complete Genome Sequence of the Cellulolytic Bacterium Bacteroides
RT (Pseudobacteroides) cellulosolvens ATCC 35603.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNY28419.1}.
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DR EMBL; LGTC01000001; KNY28419.1; -; Genomic_DNA.
DR RefSeq; WP_050753601.1; NZ_LGTC01000001.1.
DR AlphaFoldDB; A0A0L6JRM9; -.
DR STRING; 398512.Bccel_3693; -.
DR eggNOG; COG2367; Bacteria.
DR OrthoDB; 9775096at2; -.
DR Proteomes; UP000036923; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000036923}.
FT DOMAIN 96..294
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 318 AA; 36154 MW; 069CBFD4EBB6B194 CRC64;
MAVNKAKRRR RLIFKRIRFL IILCILFFIG FQVNKVLSGE NIIEDVLAFA QQFSKVDSIK
QAEEETDNFK VISSERTEKI KSTLLGYLKG VDGHYGVYYY NLFTNESFGI NEYEEFVAAS
TVKVPINLYL FEKIKSGDVN LTGTLKYLRN DYEGGTGIIQ TESFGKKYTI RQLSKLSITH
SDNVATNMLL RFIGIGNVKN YMRQIGGTVV NDGKNVSCPR DMGIYMKCVY EFCNNNSDLG
KEFMDNLLNT KFNDRIPALL PQDIKVAHKI GTQVNTINDV GIVFTDRPYI ISIMSKEVDE
NTAPQVVAKI SKIVYDLE
//
