ID A0A0L6JSG0_9FIRM Unreviewed; 836 AA.
AC A0A0L6JSG0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=Bccel_3939 {ECO:0000313|EMBL:KNY28665.1};
OS Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Pseudobacteroides.
OX NCBI_TaxID=398512 {ECO:0000313|EMBL:KNY28665.1, ECO:0000313|Proteomes:UP000036923};
RN [1] {ECO:0000313|Proteomes:UP000036923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2933 {ECO:0000313|Proteomes:UP000036923};
RA Dassa B., Utturkar S.M., Klingeman D.M., Hurt R.A., Keller M., Xu J.,
RA Reddy Y.H.K., Borovok I., Grinberg I.R., Lamed R., Zhivin O., Bayer E.A.,
RA Brown S.D.;
RT "Near-Complete Genome Sequence of the Cellulolytic Bacterium Bacteroides
RT (Pseudobacteroides) cellulosolvens ATCC 35603.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNY28665.1}.
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DR EMBL; LGTC01000001; KNY28665.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6JSG0; -.
DR STRING; 398512.Bccel_3939; -.
DR PATRIC; fig|398512.5.peg.4119; -.
DR eggNOG; COG0210; Bacteria.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000036923; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000036923}.
FT DOMAIN 13..295
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 296..559
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 836 AA; 96798 MW; 6EC8916EE1611D30 CRC64;
MDFTSILRDK YNIDLNEQQA EAVNNIHGPA LLLSVPGGGK TTVIVSRVAN MILNHNIDPG
KILTLTFSRA SASDMKNRFK KIFGNDIVSD VQFSTIHSFC YSVIDAYVRG TGKPFPKVIE
GSENEQSKAY LLKKIYLEVN NEYINEDTLE DLSSTISYVK NMLMDLKEIE ELETSMENFP
DIYNAYEKYK REARLIDYDD MLTGTYMLFK QNKEMLNIFR NKYHYINVDE SQDTSFAQHE
LIKLMASPKN NIFMVGDEDQ SIYGFRAAFP QALLDFDKTY TGAKIMLMER NYRSTECIVK
PANMFIKQNR DRFDKNMFTE KEKGNTIEFV SLKDRNSQYD HILNSVKKFG NSSQCAVLYR
NNISAIPLVE FFDRNGVSFY LKETNIHFFK HWMVTDILSF IKLGLNLLDT NSFTQIYYKM
NVFLSKEMIQ YVLSNIGEYR DIFDALMSYP GINQRTRREL AEIYKDIKRM TALKPFDAIE
FIEKDLNYKL FIRKMCKEKG YSQESLNQVM DALKTISEKC KTYDDFFRRL EHLQEVIGNS
KNNRYGHSVI LSTIHSSKGL EFDNVFIIDL IEGQFPTAKS ISDCDEGDRL LMEEEVRLFY
VGMTRARKHL EIITFDTSNK RKVPVSRFVK QLLKAQRTAN FHKTSIGGNK LKKSGVPEDI
AGAMVEHIKF GVGEVIYTDK HKGTMKVKFH DVGDKILAVN TCIEEGLIKV LEESRSTHQV
IENNSLDAYS IEELRELALE IGNTGKTRQL LTELFWHEDY EVRRRACSAA SKLKDSEVTK
SIVPCLYAPE PQIRQYALKA VLKSKCKDMV HHVKKVLENE DKYYNIDLCQ KILDKL
//
