ID A0A0L6TE08_9BURK Unreviewed; 237 AA.
AC A0A0L6TE08;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=RNA polymerase sigma factor FliA {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=RNA polymerase sigma factor for flagellar operon {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=Sigma F {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=Sigma-28 {ECO:0000256|HAMAP-Rule:MF_00962};
GN Name=fliA {ECO:0000256|HAMAP-Rule:MF_00962,
GN ECO:0000313|EMBL:KNZ34389.1};
GN ORFNames=AD742_03225 {ECO:0000313|EMBL:KNZ34389.1};
OS Methylibium sp. NZG.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=1686064 {ECO:0000313|EMBL:KNZ34389.1, ECO:0000313|Proteomes:UP000053102};
RN [1] {ECO:0000313|Proteomes:UP000053102}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bi G.;
RT "Draft Genome Sequences of the MTBE Degrading Bacterium Methylibium sp.
RT NZG.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. This sigma factor controls the expression of flagella-related
CC genes. {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. FliA subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNZ34389.1}.
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DR EMBL; LGRD01000002; KNZ34389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6TE08; -.
DR STRING; 1686064.AD742_03225; -.
DR PATRIC; fig|1686064.3.peg.524; -.
DR Proteomes; UP000053102; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.20.140.160; -; 1.
DR HAMAP; MF_00962; Sigma70_FliA; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR012845; RNA_pol_sigma_FliA_WhiG.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR028617; Sigma70_FliA.
DR NCBIfam; TIGR02479; FliA_WhiG; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF7; RNA POLYMERASE SIGMA FACTOR FLIA; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000313|EMBL:KNZ34389.1};
KW Cilium {ECO:0000313|EMBL:KNZ34389.1};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00962};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00962}; Flagellum {ECO:0000313|EMBL:KNZ34389.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053102};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082, ECO:0000256|HAMAP-
KW Rule:MF_00962};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00962};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00962}.
FT DOMAIN 204..230
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT DNA_BIND 205..224
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT REGION 13..85
FT /note="Sigma-70 factor domain-2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT REGION 183..231
FT /note="Sigma-70 factor domain-4"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT MOTIF 40..43
FT /note="Interaction with polymerase core subunit RpoC"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
SQ SEQUENCE 237 AA; 26919 MW; 5DC346C4A228A692 CRC64;
MYTAKGQLDT NAKLKQYSPL VRRLAHQMIA KLPANVEFDD LVQVGMIGLA DALNRFDAAQ
GVQFETFATQ RIRGAMLDEL RGTDYLSRGT RKQQRTIESA VQKLEQKLGR APIESEIAKE
MGLALAEYQE LLGRVRGTQL VYLEDMTGVD GDNDYLDRHV GDDALNPLAQ LQDVRMREAL
IEAIKNLPER EQHVMSMYYE HDMNLKEIAA VIKVTESRVC QLHSQSIARL RVKLRAY
//
