ID A0A0L6VFV5_9BASI Unreviewed; 898 AA.
AC A0A0L6VFV5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Protein HIR {ECO:0000256|RuleBase:RU364014};
GN ORFNames=VP01_1823g4 {ECO:0000313|EMBL:KNZ58980.1};
OS Puccinia sorghi.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=27349 {ECO:0000313|EMBL:KNZ58980.1, ECO:0000313|Proteomes:UP000037035};
RN [1] {ECO:0000313|EMBL:KNZ58980.1, ECO:0000313|Proteomes:UP000037035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RO10H11247 {ECO:0000313|EMBL:KNZ58980.1,
RC ECO:0000313|Proteomes:UP000037035};
RA Rochi L., Burguener G., Darino M., Turjanski A., Kreff E., Dieguez M.J.,
RA Sacco F.;
RT "Next Generation Sequencing and Analysis of the Genome of Puccinia sorghi L
RT Schw, the Causal Agent of Maize Common Rust.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for replication-independent chromatin assembly and
CC for the periodic repression of histone gene transcription during the
CC cell cycle. {ECO:0000256|RuleBase:RU364014}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364014}.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family.
CC {ECO:0000256|ARBA:ARBA00007306, ECO:0000256|RuleBase:RU364014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNZ58980.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LAVV01006641; KNZ58980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6VFV5; -.
DR STRING; 27349.A0A0L6VFV5; -.
DR VEuPathDB; FungiDB:VP01_1823g4; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000037035; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR031120; HIR1-like.
DR InterPro; IPR011494; HIRA-like_C.
DR InterPro; IPR019015; HIRA_B_motif.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13831; MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; 1.
DR PANTHER; PTHR13831:SF0; PROTEIN HIRA; 1.
DR Pfam; PF07569; Hira; 1.
DR Pfam; PF09453; HIRA_B; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU364014}; Nucleus {ECO:0000256|RuleBase:RU364014};
KW Reference proteome {ECO:0000313|Proteomes:UP000037035};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364014};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|RuleBase:RU364014};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364014};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364014};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 14..46
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 80..104
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 130..162
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 174..205
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 625..741
FT /note="Protein HIRA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07569"
FT REGION 378..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 898 AA; 99975 MW; 3EE17FA78F52F0E6 CRC64;
MRVIKPNWVI HPDDKGNPQT IFSAHVHPDG TRLATGSIQN LVKIWSTSPI LDPAKEEAAD
RLLSTMEGHD GNHLHLNRAV LCVRWTFSGT FLATGSDDSI IMVWLRCPGQ SKSFGSKTTN
IEDWKCFKRL AGHTSDVQGL AWSEDDQYLA SVGLDNLVLI WDCLDSSFFL LKRLDLHQGH
VNGVVWDPVG QYLATQSDDR TVKIWRTADW KLEADIKQPF INSPHSFFRR LSWSPDGAHI
VTPNAMNGPV FVSAVIDRQV WTSDISLVGH ENVVQVAAYN PLLFHTDKPQ SDQPSTTAAV
IALGARNSIS IWHTFSRAPI VVLHDVFDRD ILDLSWAADG ITLYACSSEG RVAALVIDEL
TSIATPVPPE IKAKRLASFN FQKPDRRTQT SRSSSTPFNV PRYPSSSIGP YYNESARPSP
QPSSSVITNP IPSADALINQ QEMTIMPNGK RRIKPTFLGT NESALYLNPV PTGQASDSLQ
VPQHTQSTKL NTPNATIPPI PHAIPALPPH PIASSSSSSS PSREPCDILH WNDAGKWGEP
IEIPNQILMK VQDNHTEIQL SCENVQGDMD VESSQVILSS ITASQKTELW KQWFPARSVT
AASVSASHLA IGLSDKSLSV YSCAGHRVMP IVMLDSPCFK LQFTDSMLMS FSLKGTVMVW
LVHRPPPPFF SLMISFFNPL CDDRDLTTFK VIGGPGKLKH ITETRGTISF TALTRSGVPI
VKVTKERLYG FQEDMKSWTV LGPTIMDEMK DKTRLDYGEI KLPARSPFLL DSAAALVTNK
SDLIICFLDY LSSFIDNRRF ESVNQLCHEL WAGSGWMFVA QIPSSSLPSF SLFFLMLPRF
RCDRHRSDPA ARHRASFQFS KADRLHLLHQ AIQILDQQPD FRWISQEYST LLKHASAP
//
