ID A0A0L6WKE8_9AGAR Unreviewed; 740 AA.
AC A0A0L6WKE8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Histone-lysine N-methyltransferase, H3 lysine-36 specific {ECO:0000313|EMBL:KNZ75589.1};
GN ORFNames=J132_02530 {ECO:0000313|EMBL:KNZ75589.1};
OS Termitomyces sp. J132.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae;
OC Termitomyces.
OX NCBI_TaxID=1306850 {ECO:0000313|EMBL:KNZ75589.1, ECO:0000313|Proteomes:UP000053712};
RN [1] {ECO:0000313|Proteomes:UP000053712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J132 {ECO:0000313|Proteomes:UP000053712};
RA Hu H., Poulsen M.;
RT "The genome of Termitomyces.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KQ412607; KNZ75589.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6WKE8; -.
DR STRING; 1306850.A0A0L6WKE8; -.
DR OrthoDB; 950362at2759; -.
DR Proteomes; UP000053712; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046975; F:histone H3K36 methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd19172; SET_SETD2; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 1.10.1740.100; Set2, Rpb1 interacting domain; 1.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044437; SETD2/Set2_SET.
DR InterPro; IPR013257; SRI.
DR InterPro; IPR038190; SRI_sf.
DR PANTHER; PTHR22884:SF413; HISTONE-LYSINE N-METHYLTRANSFERASE CG1716-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF08236; SRI; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KNZ75589.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053712};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KNZ75589.1}.
FT DOMAIN 1..53
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 55..172
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 179..195
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 496..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 613..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..668
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..698
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 84090 MW; 59AFF8F766CF5E70 CRC64;
MTCDCIFNPA TDHPDSACGH DSDCINRLTQ VECLMDDCRC RSHCRNQRFQ KREYANIDIV
QTELKGFGLR AESFLRKDTF IYEYVGEVVS PVSFKKRMRE YAEEGIEHFY FMMLQKDEFI
DATKSGGIGR FANHSCNPNC FVARWTIGQH VRMGIFAKRD IQKHEELTFN YNVDRYGHQA
QTCYCGEPNC VGFIGGKTQT DAATMDDLVF DALGITDEAD LMEVKGNKKK RGKKIDDPDF
MPTMKPLVEK DIPKVIQAIR QTQSRKVLLK LLTRIKLTED QAALRQIMRL RGFSLMTNVL
EDHQSDVELI NLALSCMSTW PLLNRNKVDD SHVIIHVRAI AATEGDKNKQ LAQSLVSHWE
TLPLYNRISK RAIPDDEEEE MKQVASFDND ELIFQQRRGL QGREIDITRT KYRPKPQIRR
RLDEGVWIPP SMVNLQSETP APASELKVSA AEFSRESIRA VIAAAAEAEV AAAKAAAAAA
DAEALAKAEA KAAARAARAA RHEMSKGEHN HHKKSKKPLT EEERETMKEK RMLKLVGAVV
VKCMSKHSRA MDHDQFKKHA KELTQIITNK EKKSSSYKEG RLEKLSDEKV VKIKKFAKEY
IAKILRKIEK SGKRLRESSL TTPPASSSAV QHTPQSHEDE DVVMDDPSME DMNIVSDSDE
DEDNEDSQEY LTIRDKDEDG PKEMTRTRLE DLPTAGHWGE MDFEESMGQS TSVRLSSDPR
RRPPSEDFTS WEPPQGPSGM
//
