ID A0A0L6Z7X8_9CLOT Unreviewed; 736 AA.
AC A0A0L6Z7X8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Lactococcin-G-processing and transport ATP-binding protein LagD {ECO:0000313|EMBL:KOA19070.1};
DE EC=3.4.22.- {ECO:0000313|EMBL:KOA19070.1};
GN Name=lagD_2 {ECO:0000313|EMBL:KOA19070.1};
GN ORFNames=CLHOM_25730 {ECO:0000313|EMBL:KOA19070.1};
OS Clostridium homopropionicum DSM 5847.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121318 {ECO:0000313|EMBL:KOA19070.1, ECO:0000313|Proteomes:UP000037043};
RN [1] {ECO:0000313|Proteomes:UP000037043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5847 {ECO:0000313|Proteomes:UP000037043};
RA Poehlein A., Beck M., Schiel-Bengelsdorf B., Bengelsdorf F.R., Daniel R.,
RA Duerre P.;
RT "Genome sequence of the strict anaerobe Clostridium homopropionicum LuHBu1
RT (DSM 5847T).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOA19070.1}.
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DR EMBL; LHUR01000029; KOA19070.1; -; Genomic_DNA.
DR RefSeq; WP_052222064.1; NZ_LHUR01000029.1.
DR AlphaFoldDB; A0A0L6Z7X8; -.
DR STRING; 36844.SAMN04488501_12914; -.
DR PATRIC; fig|1121318.3.peg.2583; -.
DR Proteomes; UP000037043; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043214; F:ABC-type bacteriocin transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd18570; ABC_6TM_PCAT1_LagD_like; 1.
DR CDD; cd02418; Peptidase_C39B; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005897; Pept_C39_ABC_bacteriocin.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR01193; bacteriocin_ABC; 1.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KOA19070.1};
KW Hydrolase {ECO:0000313|EMBL:KOA19070.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022807};
KW Reference proteome {ECO:0000313|Proteomes:UP000037043};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..138
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 171..450
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 485..719
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 736 AA; 82022 MW; 2EFF20DF03F7EF65 CRC64;
MKNPFKKYTC IKQHDLKDCG AACLATISKQ YGLSIPISKI REVAGTDKLG TSAYGVIKAA
ESLGFTAKGV KASKPDDIFS QFPLPAIAHV VMEGNLLHYV VIHRINKEEL LIADPGKGIV
KYKPEDFFKI WTGVLILLVP SAKFKKGDET KGLFSRFLGL LKPQKGLLIN IFFTSLIFTL
LGILGSFYFK VLVDDILQYS LKKTLHILSI GVIALNIFKI LLNAFRTQLL MYLAQKIDIP
LMLGYYEHVI GLPMNFFGTR KVGEIVSRFN DATKIREAIS GATLSIMIDT LMAIAGAVIL
YTQNHLLFGI TLIPVVLYAI IVFSFNKAIK DVNRETMEDN SKITSYLVES LNGIETIKAF
NAEREVNFET EKRFIKLIKS VFKNGLINNV QASIKGTVKS IFGIAILWIG AYECMEGRLS
VGELLAFNSL LAYFLDPIEN LINLQTQLQT AIVAADRLGE ILDLGLEKAP NEDKKIKPSS
LVGQIEFKNV DFRYGTRQLI LENISLSIAP GEKLALVGES GSGKTTLSKL LMNYYQCEKG
EVLINGYNVK DINIEILRDK IACISQDIFL FSGTITENLS LGNPSLELEA IIEACKKAKI
HDFINSLPLR YDTLVEENGS NFSGGQKQRL AIARAILRTP EILIMDEATS SLDSITEKAI
EKTMYDLSKN ITTIIIAHRL STIMRCDKIC VLEKGKIVEY GTHNSLMKEQ GRYFQLWRDQ
LPDNYEAVSA KEVILA
//
