ID A0A0L6ZAG5_9CLOT Unreviewed; 447 AA.
AC A0A0L6ZAG5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=GABA permease {ECO:0000313|EMBL:KOA19964.1};
GN Name=gabP {ECO:0000313|EMBL:KOA19964.1};
GN ORFNames=CLHOM_15290 {ECO:0000313|EMBL:KOA19964.1};
OS Clostridium homopropionicum DSM 5847.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121318 {ECO:0000313|EMBL:KOA19964.1, ECO:0000313|Proteomes:UP000037043};
RN [1] {ECO:0000313|Proteomes:UP000037043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5847 {ECO:0000313|Proteomes:UP000037043};
RA Poehlein A., Beck M., Schiel-Bengelsdorf B., Bengelsdorf F.R., Daniel R.,
RA Duerre P.;
RT "Genome sequence of the strict anaerobe Clostridium homopropionicum LuHBu1
RT (DSM 5847T).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOA19964.1}.
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DR EMBL; LHUR01000021; KOA19964.1; -; Genomic_DNA.
DR RefSeq; WP_052221094.1; NZ_LHUR01000021.1.
DR AlphaFoldDB; A0A0L6ZAG5; -.
DR STRING; 36844.SAMN04488501_1122; -.
DR PATRIC; fig|1121318.3.peg.1538; -.
DR Proteomes; UP000037043; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR PANTHER; PTHR43495:SF5; GAMMA-AMINOBUTYRIC ACID PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037043};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..444
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 447 AA; 47567 MW; 1F904C1E5E887A4E CRC64;
MENKKGGLSP LHLSMMALGT VIGGSFFLGS SIGIKAAGPS IILVYLLVGI LVYFILYALS
EMTVADPAPG SFRTFAERAF GPGVGFVVGW VYWTGLILAM SSEATAVSVF LRIWFGNIPI
PILGSGIIVL ITVLNLLGAE KLSKLESSLS AIKLLAIAGF IVIAIAIIIG ILPNIPSTGL
GEIQREALVP SGISGVLGSA LIVMFTYAGF EVIGLAASEA ENPHVTIPKA ITYTVVGLVG
LYSIAIAVLL PLINTNKLTG DASPFVLALE SRGISWAARV MNIILVIAIL STMLAAMFGL
GRMLRSLAEE GHAPRILKDT GEIPYKGIIF SGISMLIGLG LGFLLPKQVY IFLVSSGGFS
LLFTYFIILI THNRFRKNHG CPPKGKCRFP GYPYTSWISS IAVIVIIASM PFIEGQGAGL
LAGLFLVIFY SSIYVIVYKK SFKVQRE
//
