ID A0A0L6ZD57_9CLOT Unreviewed; 765 AA.
AC A0A0L6ZD57;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=DNA translocase SpoIIIE {ECO:0000313|EMBL:KOA20887.1};
GN Name=spoIIIE {ECO:0000313|EMBL:KOA20887.1};
GN ORFNames=CLHOM_04750 {ECO:0000313|EMBL:KOA20887.1};
OS Clostridium homopropionicum DSM 5847.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121318 {ECO:0000313|EMBL:KOA20887.1, ECO:0000313|Proteomes:UP000037043};
RN [1] {ECO:0000313|Proteomes:UP000037043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5847 {ECO:0000313|Proteomes:UP000037043};
RA Poehlein A., Beck M., Schiel-Bengelsdorf B., Bengelsdorf F.R., Daniel R.,
RA Duerre P.;
RT "Genome sequence of the strict anaerobe Clostridium homopropionicum LuHBu1
RT (DSM 5847T).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOA20887.1}.
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DR EMBL; LHUR01000011; KOA20887.1; -; Genomic_DNA.
DR RefSeq; WP_052220074.1; NZ_LHUR01000011.1.
DR AlphaFoldDB; A0A0L6ZD57; -.
DR STRING; 36844.SAMN04488501_104245; -.
DR PATRIC; fig|1121318.3.peg.478; -.
DR Proteomes; UP000037043; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000037043};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 431..622
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 448..455
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 765 AA; 85254 MW; C2D1D6DE99F1944E CRC64;
MARKNSKSNK KTPESTNRFG NDIKGILLIT VGVLMLLSVF ITNSSGLIGI TIKKTFIALM
GLGSYFFPLI IILTGVSYII KNGKVIFNNR FYGIILFITN SLMLIQMINI NKYYINNDIL
QGIKKIYSNP SIFHGGIITY LIDIPLYKLF GSIGSYFIMT AIYIISIVLI VEINIKDIFM
YFRTPNKDEE SIKQNNKLES KIEDNQSSFI KNINHKIKMV NFMKSTEGDV SKDNVENREI
KVFEPRVAFS KNNENLKEKS TKVLDKNSDK SEEGLSEELN KEINEGLTKN EVAYIFPPLQ
LLNYNENITT NKSSKKELIN IASKLEETLS SFGVEAKVMQ VTKGPSVTRF ELQPSAGVKV
SKITHLSDDI ALSLAASSIR IEAPIPGKSA VGIEIPNKET LPVFLKEVIE SEEFRNFNKN
IAFAIGKDIG GKCVVADLSK MPHLLIAGAT GSGKSVCINT LIVSLLYKYT PEEVKLLLVD
PKVVELNIYN NIPHLLIPVV TNPKKAAGAL NWAVTEMSRR YNLFAENSVR NIEGYNELYN
KGKIESKLPW VVIIIDELAD LMMVCPGEVE EYIARLAQMA RAAGMHLVIA TQRPSVDVIT
GVIKANIPSR ISFAVSSQID SRTIIDSAGA EKLLGKGDML YYPVGESKPI RIQGAFISEE
EVEKIVNFIK SQKSEVTYEE GIIDEINSSV EKGDSESDDL LDEAIEIVLE SGQISTSFLQ
RRLRIGYNRA ARIIEQLEDK GIISGKNGTK PRQVLLENDS LKNNK
//
