ID A0A0L6ZE95_9CLOT Unreviewed; 332 AA.
AC A0A0L6ZE95;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Isocitrate dehydrogenase [NADP] {ECO:0000313|EMBL:KOA21304.1};
DE EC=1.1.1.42 {ECO:0000313|EMBL:KOA21304.1};
GN Name=icd_1 {ECO:0000313|EMBL:KOA21304.1};
GN ORFNames=CLHOM_04340 {ECO:0000313|EMBL:KOA21304.1};
OS Clostridium homopropionicum DSM 5847.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121318 {ECO:0000313|EMBL:KOA21304.1, ECO:0000313|Proteomes:UP000037043};
RN [1] {ECO:0000313|Proteomes:UP000037043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5847 {ECO:0000313|Proteomes:UP000037043};
RA Poehlein A., Beck M., Schiel-Bengelsdorf B., Bengelsdorf F.R., Daniel R.,
RA Duerre P.;
RT "Genome sequence of the strict anaerobe Clostridium homopropionicum LuHBu1
RT (DSM 5847T).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOA21304.1}.
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DR EMBL; LHUR01000010; KOA21304.1; -; Genomic_DNA.
DR RefSeq; WP_052220032.1; NZ_LHUR01000010.1.
DR AlphaFoldDB; A0A0L6ZE95; -.
DR STRING; 36844.SAMN04488501_107181; -.
DR PATRIC; fig|1121318.3.peg.439; -.
DR Proteomes; UP000037043; Unassembled WGS sequence.
DR GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KOA21304.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037043}.
FT DOMAIN 4..328
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 332 AA; 36060 MW; F2B624A5B7F5A4F3 CRC64;
MTHCVTLIPG DGIGPEVMIA TRAVIDASEV DISWEIVEAG RKVIDEFGTP LPNYVIDSIK
KNKVAIKGPI TTPIGEGFRS VNVGLRQALN LYANVRPVKT YAGIKSRYDD VNLIIVRENT
EDLYAGIEHS IGDVAAESIK IITRAASERI AEFAFKMARK EDRKRITVVH KANIMKLSDG
LFLKCAKEVA ERNKDIQFDD MIVDAMSMKL VQNPEKYDVI LMPNLYGDIL SDLCAGLVGG
LGVVPGANIG DDVAVFEAVH GSAPDIAGKN IANPIASILS GVMMLRYLGE YEAADRIDIA
LAKVLEEGKV ITSDLGGNAK TMEFAEEIIR NL
//
