ID A0A0L7K5L1_PLAFX Unreviewed; 440 AA.
AC A0A0L7K5L1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Choline kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFHG_00406 {ECO:0000313|EMBL:KOB58658.1};
OS Plasmodium falciparum (isolate HB3).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=137071 {ECO:0000313|EMBL:KOB58658.1, ECO:0000313|Proteomes:UP000054289};
RN [1] {ECO:0000313|EMBL:KOB58658.1, ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HB3 {ECO:0000313|EMBL:KOB58658.1};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Kodira C., Zeng Q., Oleary S., Yandava C., Alvarado L., Wirth D.,
RA Volkman S., Hartl D.;
RT "The genome sequence of the Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH671923; KOB58658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L7K5L1; -.
DR SMR; A0A0L7K5L1; -.
DR EnsemblProtists; KOB58658; KOB58658; PFHG_00406.
DR VEuPathDB; PlasmoDB:PfHB3_140007600; -.
DR OMA; IETSIDY; -.
DR Proteomes; UP000054289; Unassembled WGS sequence.
DR CDD; cd14021; ChoK-like_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054289}.
SQ SEQUENCE 440 AA; 52207 MW; B9D89E87429B7484 CRC64;
MESKICDPIG LDKNKFRKVE EENEENSKIV ENGQMTYNDD LEMFTTIQLN QEIDIRKNPF
PLHMINQKND IPLCAQEFSK LTDPLYIKKI CLEKVHDWSR CNEDDVCVNQ ILSGLTNQLF
EVSIKEDTAI EYRITRRHVL FRIYGKDVDA LYNPLSEFEV YKTMSKYRIA PLLLNTFDGG
RIEEWLYGDP LSIDDLKNKS ILVGIANVLG KFHTLSRKRH LPEHWDKTPC VFKMMDRWRL
AVSNYKNLDK VTLDINKYIQ ESHKFLKFIK IYTQIENIAN DIVFCHNDLQ ENNIMNTNKC
LRLIDFEYSG YNFLSADIAN FFIETTIDYS YNAYPFFIIN KKNYISYESR ILFVTTYLSK
YLDDSTAASD QDIIDQFLEA IEVQALGLHL IWAFWSIIRG YQTKSYNEFD FFLYAKERLK
MYDEQKQYLM SKNIIKDYDD
//
