ID A0A0L7K8Z2_PLAFX Unreviewed; 2730 AA.
AC A0A0L7K8Z2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Cell cycle associated protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFHG_01593 {ECO:0000313|EMBL:KOB59873.1};
OS Plasmodium falciparum (isolate HB3).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=137071 {ECO:0000313|EMBL:KOB59873.1, ECO:0000313|Proteomes:UP000054289};
RN [1] {ECO:0000313|EMBL:KOB59873.1, ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HB3 {ECO:0000313|EMBL:KOB59873.1};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Kodira C., Zeng Q., Oleary S., Yandava C., Alvarado L., Wirth D.,
RA Volkman S., Hartl D.;
RT "The genome sequence of the Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH671947; KOB59873.1; -; Genomic_DNA.
DR EnsemblProtists; KOB59873; KOB59873; PFHG_01593.
DR VEuPathDB; PlasmoDB:PfHB3_120025200; -.
DR OMA; PYINHFL; -.
DR Proteomes; UP000054289; Unassembled WGS sequence.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR22870:SF463; E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED; 1.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF13540; RCC1_2; 1.
DR SMART; SM00015; IQ; 4.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054289};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 2301..2355
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REGION 479..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1491..1514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2508..2530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..525
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2730 AA; 326841 MW; 8E4E50335654AC23 CRC64;
MDDSSSLNRK LYFLNLDKEI GAGGSETNSD DDDNNKLINY FNIKKTNDLY LKSNKKNNKQ
CILKDLHFNG DYLIKKKQTK KIQKKNGHFV LPNKYDYILK KKSDIFHTDE FISKSYHLNN
VHDIYYSYKE ESDLCDILIK RYKENLYVTT FNNMLILINP TDNVMAFYKL LFKPNNKNNY
IINTFVRFFL EKKLQETTVE YQEVNDSEDL TNSSLDYEKE ENKSDYSSNE IKNAINYINK
KHNITINNQF NFNQIKKKRK KKKLVDIKKD LCIKSNQEFV QMNTNVLKKN VINFNMLYNI
NAFFNEKEEN YEENKSNHKE NIYSSHVEMN NYNTHVNVYP NSFEKATSET SYKLKTYNEQ
NKLLFIYGEN YSNQNVINKY IFKHIIKKYQ EQEDIHTSIK HKKKKKKNLY DLYKRIMNIL
KLFYNEDCYN FIIHFSDNQE VVSFNIIPFM LNNTCNVTNI CTKMSDVFCE LLNNANMHNK
DNDNVEKNEK NDQKMKDMSN RKNNIRSNDN IKTKNSREKK NEHSNNSNEF LYNDKHNNIN
NSDEYNNENN FINIPYIFFF LLQSIMLNSN HTYVKPLNLH TLDIKKIYLN YIESHEIELN
ESDMETTFSN FSQLGFSLDE IISINKIIFS IIFINIYIKI KQCLKMNEKE TLKILQIQLI
EISDFMKLRK KKINKNNSKY GLLNNGKKCS LPQFINFNED NYLSSGFSSL SETENIHLFN
NDMTKENNKK KNSSIDDFQG ARLKTNDSSN VNVNGKKLDD NPYDSQKDVN KMENEYRKSE
NEVNHLGEVN KQIVSNNIKN DNNNNNNNNN NNNNNNNNSS SSNNNNNNNN NNNNNNNNSN
EYYYTNEPIN MYKKDNKKYK EPIDKKGNKY FIVFAGHILE EYISSLLNID INLFIHILNN
NIKLKSLCSN MFYRLKIKIV KKINEYLKNV VRNELIHHSL YLYCNGGIIQ NILEKNEDVN
KYYKNKEKNH FNELINNIYN ELLHSYYLKM SMFNIDSCIM HMITTLDNKQ NNYEDALLCT
LHNYGKKGNL YNNNINYKND TDQIIPNFLC NNIYLGENRI LHMLEKYSTK FSSVMDLHYN
LYNKEKDSPS YILIKSEYYK ILSLFYLAIK NITELYNKYI INNNNKNNNS DNINNIICKC
KYICNCKYKY NYSLDKQLYH IDDEKCMHDI LLKYFQYLSN DSITKKKNIH GKRKRRRKYM
KYNFCITHYN DKKIEYTCNN MIFDNIKDIY IFKDIIDIIE NSDMLFLRSM FFENNTLPLK
SVKSDFFLYN EMNFFINIIN NTFDKFYFLV INESEKKQKD IFIPKYITNC IKHNESTTYD
HYASTTSQSN LYKRFSLTLN KSFVHNNNIK SFKSLFLHMD SVRTDNITNF SDFSKKKINK
DHITFVINMF NLKNIFNYQQ QYLYYCIPYI CFIKKYILFC AYVSKEKDLI KLLNYYEEKY
YKPNNSYNTH GKDTKNIIYN SSNMKDNLSN NDTNHNILNQ SINIYKEKMY NNQNNNKNKN
KNKNKNKNKN KNKKNIYNDT TNFIYLNKLS IEEMKDMCTL ILYNFNISTN IIHFQNYLFI
KKSLYFLLEN MKNEYLKYII PFIRKIENSY ISYKNKKIKF SYRNKIIVIQ NYMRKYLFFH
ELQKKERKKN LLTSFIIFYS YLLKHKNMEE TKETLEYYKE TFMSKEKKLI QHAACVYIQS
WFRKIIQQRK YKAMKLEILK THAREKISTA IKTYITQIKM IKNLNEVLIP NRCATLIQSC
FRRYRCMVQY EKKMYLKICF LSIKRKYMAY TNVITKMNYH YLIKNIYRKN FIKNHLKIPE
AVVKIQSKYK AYVVRKQYNM LRDAIYFTQS YIHTCIERIK YEQLKKSVIT IQVWWRNFYK
LRKIFQNFPL NIYNSEYEKT KYYFLHKKNF PNYYYYILKE QKAMKLLTYN ILLKQWYFFY
FKKFQKKNHL FNIIFNLKLY KNISYYYLLP WAYKINAILK MIHMKQMFKI CTTNYYQNTI
LNIPLFETIQ IFVGKTHTIL LINQSVNKDN NNNNNTEQIV SQGYNKNSKQ FYTKYVYSIG
SNDCGQLGYY DLSSSPFLYH SNVLNDKWDH VDINEDENNK LNPINEKIEH PVKKDIYINT
MDDHTKIDNL FNDHNDNSDN DNRKTTLGSL HKESMDNNST SIFSTHKSSV DNNIINNAYN
NNNKLYNNKH FSDQYNNIHI SHKEEITNNK TKFKNVNDNY LRNLQHLEFQ YKKKYTISKK
NFGDMFNENV NDIIDYKIID KEDDKYSKNI TNNNKYEYDF NIDKSHKGKK IVEFTKLINE
TNKILNICCG SEHTLALSEN GNVYSWGNNA YGQCGQKYEK HIIRYPKIIK YFLKNNILIK
NISCASYHSG YITKSNDLYI SGNFFFINLK YFQNNIYEPI FLISGCLNIT CKDSFNISLR
TNKNSFYLWG NNYKCILGIN KKKLANLDEI SIYPLNNICP NIIVKKIACS DNFVCIITTL
ATTNNYTMFM WGQFSHIEKK ENQENDTKSV LNTNNFFNKF RMKAKMNNTK NDNQNNDINN
NNNNNNNNIS KNKKNMIYIA KPTPVYNEIW EQNEAVDVCC DLDEIMVLMS NLYLYGFSSV
EILGGDKKKV IANEPKVFFN HFNRKPKVEK KENDIKFEEP EIHENIKVLN PVLYMFKYFK
PSYFNVKKIQ CSYNKNSLSI MNVTMGEYEI PKIKQNLEYV TPSGDIVNFP EKIKEAILEK
AKKESNKWIK SNDDPYINHF LIQNSSDSGN
//
