ID A0A0L7KA89_PLAFX Unreviewed; 3312 AA.
AC A0A0L7KA89;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=SNF2 helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFHG_01630 {ECO:0000313|EMBL:KOB59829.1};
OS Plasmodium falciparum (isolate HB3).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=137071 {ECO:0000313|EMBL:KOB59829.1, ECO:0000313|Proteomes:UP000054289};
RN [1] {ECO:0000313|EMBL:KOB59829.1, ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HB3 {ECO:0000313|EMBL:KOB59829.1};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Kodira C., Zeng Q., Oleary S., Yandava C., Alvarado L., Wirth D.,
RA Volkman S., Hartl D.;
RT "The genome sequence of the Plasmodium falciparum HB3.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH671946; KOB59829.1; -; Genomic_DNA.
DR EnsemblProtists; KOB59829; KOB59829; PFHG_01630.
DR OMA; KQSMGGI; -.
DR Proteomes; UP000054289; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623:SF14; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054289};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1303..1479
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1612..1768
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1080..1107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1979..2000
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2087..2263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2278..2302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2359..2400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2497..2558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2577..2656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2673..2890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2923..2956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3023..3085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3159..3184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3202..3225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1017
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2087..2103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2107..2122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2123..2146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2147..2167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2168..2205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2208..2228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2229..2263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2359..2387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2536..2555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2595..2614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2617..2631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2642..2656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2690..2712
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2713..2733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2765..2783
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2807..2824
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2837..2877
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2932..2955
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3024..3041
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3053..3071
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3312 AA; 379481 MW; 90D3782074C70454 CRC64;
MNNNSNMREA VPHFTTDNKN NESENSIMKK NLTSNFMGQV NNNKNSTCSA TYLNNTNNMN
ISKDKNYNSN INNDNASISI TNSLLNNDQN MSMRPQMGMN KNCGGGLHNS YQKSLLSSYN
MNNMSMNHLM NNSMNRYNSL NNNNYPHQDM NQTNMHMTNI KSALQNNNND MKGNNMKQNG
YMNNNNMNYQ RNDMLMRNNS NSFNMAGNFY PYMNNNNNNN NNSNNSSNNN NNNNNNSNNN
NSNNNNSNNN NNSNNNSSYY GASSVMGLNS NTNNMMNNTS LNNNFNNNNN MGAENNNKTM
SLLNKTGGGS LDNNNTSHQP MKSLQSTINL NNRNINNMNN VSGNNNSNSI NSNNINSNSV
FNNNNSKGVG SFISNPSMNV KGISSVCNIA SYRNSTSFEK TNSIIDNNMR YMNVYNKMGY
NNNVNDYHQT YDNSSALNDN LNNKDKKGKE EGNGDNEKNG TSNMMNNDNN NNNNNNNNIG
DSKLRKKRGE SFNTKGIIGN NAESMIFKTY NKNNDMDENN NKYGMNKGNI EMMKDSSANV
SKNDNIMNNL SNNNIGGTTS NPYNLYPNFN LKYPMNMDMF NNNNNNNNNM SSFNMLNRNL
MNSHLNNNNN NNNNNNFSSM SMFNNMGDNN NNNSSSSSSI LYNNMNNFNL LNAYNNNDNN
NNMNMNSIGV GLNRYNAYKN MENIKNYNEA LMSGNVGGAG NNNLSNLMNM NNFNNMGYLN
GRSCMNDMNM RLLNNSKFLP GNMGLSNNNY MNDHQYMNNN ENLYGMMYNN MDDKNNMKYS
RKGSLGAKQQ QQQQQQQQAL STSKGKKSAS QKKKKSKNAT ATINGLQGGE EKLKKGVSGK
IGDDFIMDNN GDLVNDGNND DNDLYVNTYV KKSTTTKSST RKSSYYYETA EDKYNEKVRK
NEKYDIFVSP NIGTIEGGRT NLRQRRKVHN YAQMEDNYFE TDEEDKRVDE EKFLLRQEKQ
SMGGIDRVLH HRKILDYDKI NSICNNPYLY INKKNKLKGN EKNSDSNDKE KSGACDDGAN
IGKDNNNDVN NEDVVKDETI KNETIKNETI KNETINNETI NNETINNETI NNENVKKENL
ADNNNNKKNE VTNVDSNKQT NNNADNDEAN AVDEFCEEED IEDINEVEFL IKWIDKSHIH
NFFCTYDYLK NFHGIKKVDN YIKKIRQSFQ KRKFMTADEI EQEKIYSEIK KQIEMDAIQA
ERIVMHKISD ITNEQVFLVK WTSCAYDQCT EETKQTLIDH GFGKLIEEYF DRESKIYGMK
AMASVWNRGP LSVTKFDPYH ETPFYLNEKK LRAYQLTGLN WIVSRMKRNL SVLLADEMGL
GKTVQTIAVV GHMLYKEKLI GPYLVIVPQS TVDNWLNEFK SWLPQANVVC YHGNAVSREL
IRTHELKKVY VPNKGYRYKF DVCITTPSIL NSVSDVELLK KMPWQLMVVD EAHQLKNRQS
KRFIELKQFM AESKLLLSGT PLHNNLEELW TLLHFLNPQQ YTYYETFQKK YNEIENTSLI
GEAKQKQLIQ LQHELHEVIL RRVKKDVEKS LPNKVERILR VELSPIQIEY YKNILTKNYE
QLAKASGGAK NSLQNICMEL KKVCNHPFLC AEPLDKDEYK ERLVYSSGKI CLLEKLLIRL
KERGNRVLIF SQMVKMLNIL SEYLTLRGFK HQRLDGTMTK EMRKKAMNHF NSKNSDDFVF
LLSTKAGGLG INLTSADTVI IYDSDWNPQN DLQAGARAHR IGQTKTVQIY RLVTKDSIEQ
TILERAKVKM VLDTLVVQGL NKKQNDNVNY VGGETGGSSN GFTREELSKI LKFGAQKLWE
KNSSKYSPQK LDEDKNAIKG VDVDLDKILE EAEINENANN ANKELSLNSE LNALQGSSNF
FNSGNSLFGN TNLVGTNGAT GGSGGIADDL LSSYNNITEF KYEPPANLKS NIYNDSTKAD
EVDEEENDKD FWDKTIPLEE RLKLKRMKEE ELLVHGPRKT RAKDMRSVLY MDHGHYYNNT
SSSHHNNNAH GNNNEDEDSD EFTIKYNDKN SKHLKKKRQR RTSTHITEKD KFRLYRSLLK
FGNPSLRLDD IQEDAKLTKV DKNVILTELN IIVETCNEIV ERVSKNEQVD DNKKEKDIVV
DGVVNNDDSK TKGSNNDVAD VNSKDGNKLK KGIEEENPDA SLNTKDEEDN NASTTGSNNI
TTISCDDSNK QDDNKKKVEE EGEKDDTLIN DTIGKEDEEG GTIGTVVSKR RRGSTLNSNS
SSVMSHGMKT RDKASKDDDN NNNNNKNDGN NKNDDDHHKN NDDSVEDELL LNQNDDDQLH
MKNNENSNDE SDGGNNKAKG IDKGKKMDAY TFFIGTNRAN ALDLCQRLKL FEALHNFIKE
QNNDNEYSFK LPLKKCEEVT GEDDENGKNN EKAQTDEKTE DENVKNNEVV ENNNNDNNNN
IPVDVMIDSS KDYLKLKLPD SIFKHIRDLT SKDVKSWTRT DDENLIRGIY VYGFGSFNEI
CADAHLNLSH MKNIKCDKIK MRCVRILRMI EEVYNNKGNE QSGGRKRRRT KNKNNANVEG
VTMDGSVKKE KRKYNTNSNN NNNNNDNNNN NNNRDVDADM DVDADVDVDV DVDADVEYNE
SSSKGHLKSG ALIKVDKGNN NNNSNTTSRL SSNRKGNHYS RRSDKNSASA IRKRRGYIKR
GTASGVSSSN VVGGTVNGNF VDELNEEVEG EDAFLETQED NELKERHKSN ENNKHHHNQH
YYNSKKSKKK KHANVDVSKD DKESKRKRGN NNKLNNEYDY YNYDNNEKEE DDEGGGTKFK
DNEYNDDVDD DDDYDDDDDD EIDPNLQRLP LRFPVIEKRK AKSTILKNAK NETIVCIESS
DSSSSTEDKS IRSKGDEYDE EDEDEDEEEE EEDDENEDDD DDDVEDEDDD EESGECDKEE
ETGKRKRRRN SRYYKSSNKY IKDNEMLDIT SVGANDEYKY EDGDNLERKK RSSKKDKKKK
KNKLKEKKNK RKRKRRKIVD ENEIMDKIKN LNINHMDYEQ QQHCIKKLVK KCIKKYKKLL
KLIKKVILLS VENGNQVNEE ENQSQVVLEH EQQEDVLSSG RGRRTRTGTR TSTRTSTRRD
MDYKKMEGGR RGGGGKTTSD VTTTNSYEKD ENMMNKSMTK ILPPEIFEKI EEFIIFIGKY
IDKFCSICKD MECREKLIQA SWEYVSKFVI IIMDGTNNKS STTNSKTNSN SSSSRTKGKV
NNTVKMNNSE VLRDMYKQWK DKKQVKGSDE NNNNDDDDNN NNNDNVIEDE KVFIEFFYAK
KASFNKNVRD RNYINNDLYS NSNELVYSKK GNKSEEPLSK VRKNELLEEN NLNINDSNES
INGEVEIKRM KN
//
