ID   A0A0L7KGX5_PLAFX        Unreviewed;       865 AA.
AC   A0A0L7KGX5;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   03-MAY-2023, entry version 20.
DE   RecName: Full=PA14 domain-containing protein {ECO:0000259|PROSITE:PS51820};
GN   ORFNames=PFHG_04349 {ECO:0000313|EMBL:KOB62578.1};
OS   Plasmodium falciparum (isolate HB3).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=137071 {ECO:0000313|EMBL:KOB62578.1, ECO:0000313|Proteomes:UP000054289};
RN   [1] {ECO:0000313|EMBL:KOB62578.1, ECO:0000313|Proteomes:UP000054289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HB3 {ECO:0000313|EMBL:KOB62578.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA   Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA   Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "Annotation of Plasmodium falciparum HB3.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000054289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA   Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA   Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Kodira C., Zeng Q., Oleary S., Yandava C., Alvarado L., Wirth D.,
RA   Volkman S., Hartl D.;
RT   "The genome sequence of the Plasmodium falciparum HB3.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH672079; KOB62578.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L7KGX5; -.
DR   EnsemblProtists; KOB62578; KOB62578; PFHG_04349.
DR   VEuPathDB; PlasmoDB:PfHB3_140057300; -.
DR   OMA; YYDNAYF; -.
DR   Proteomes; UP000054289; Unassembled WGS sequence.
DR   Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR   Gene3D; 3.90.182.10; Toxin - Anthrax Protective Antigen;domain 1; 1.
DR   InterPro; IPR036943; FN_type2_sf.
DR   InterPro; IPR037524; PA14/GLEYA.
DR   InterPro; IPR011658; PA14_dom.
DR   Pfam; PF07691; PA14; 1.
DR   SMART; SM00758; PA14; 1.
DR   SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR   PROSITE; PS51820; PA14; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054289};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..865
FT                   /note="PA14 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005572563"
FT   DOMAIN          215..383
FT                   /note="PA14"
FT                   /evidence="ECO:0000259|PROSITE:PS51820"
SQ   SEQUENCE   865 AA;  100020 MW;  FB402B7FBED63322 CRC64;
     MKYINTICFV LIFLSSKCNT QNYDKENLKK LTEYRQQHRK TVDGRLCAAA FVQDDQTYTD
     CTRATDPNGI TGKEWCYVEV QLIGKGNRDW DYCKGVINYD VVRSKARTFF QSKSNELLDA
     VNKLDFEYKK LVGIYEKYKE VCGNASDLLK KKIQDINDLA KNSSRNINRL LLQATSLSDT
     GNKIIELEEE AEKNRKSYLE NKKNCSMQKG YVVEEKADGL MASYYNNAYF SGYPTAIHND
     KYINFIWDTG IPIENIPYQH FSIRWDGYLK IPESDNYIFS VDHDCGIRIF LDNSPIIVDN
     MPFPKEEESE EIRPISIQSF DKMNSKVHKT NSEKLGLIGG KKYKIRIEYF HLSTMKFANP
     HISHIILYWK SNNIMEEIIP SNYFFQGNVS TPLRITELNG DTFEIFPLQN GVHAFMNNMS
     YLINDIPTIH EKLKAIRTLY NFNKNIIKFR INVYCIVYIA IPKEQKKNIP LNDITKKEFT
     NTKETLSIYE VQQNSNNSST EQKIYYIYSS QYNEGEVIIS LPTPTTFLLF VQPSDLRSGD
     TCKGYVQPVS LTSSDYFHSC YTSSYESQMF DCNAGFSGNN QEKEYSTWKT AQNKSLGQYV
     SINFKYDIDI HSFTFKTLNL SNNNTINELS LYFPSIKNPE IFSISPGHHH YVLKTPIKTN
     TVKVVISKVN NPKAQTGGNI TFYGIPCIDI KNQEKESDKK KSQYEINIFF RSKNVHISKP
     FNWIIDNGMK KSDHGFFKYG WDLLPTPIDL RYLDKKDPTH AGISFVPYEC NNTNTCNKQT
     FNKWSIDLIH EGTYSVTIEI GSPTGKQEIN SIKVNNEIFI NNIFLKPKQY TKVTANIVIK
     ENKTLELTTN TNTVIQSIQI LFLHN
//