ID A0A0L7M2G7_PLAF4 Unreviewed; 552 AA.
AC A0A0L7M2G7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=PFDG_02986 {ECO:0000313|EMBL:KOB87013.1};
OS Plasmodium falciparum (isolate Dd2).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57267 {ECO:0000313|EMBL:KOB87013.1, ECO:0000313|Proteomes:UP000054282};
RN [1] {ECO:0000313|Proteomes:UP000054282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum Dd2.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Kodira C., Zeng Q., O'Leary S., Yandava C., Alvarado L., Wirth D.,
RA Volkman S., Hartl D.;
RT "The genome sequence of Plasmodium falciparum Dd2.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR EMBL; DS016427; KOB87013.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L7M2G7; -.
DR EnsemblProtists; KOB87013; KOB87013; PFDG_02986.
DR OMA; LIVYTHW; -.
DR Proteomes; UP000054282; Unassembled WGS sequence.
DR CDD; cd02961; PDI_a_family; 1.
DR CDD; cd02995; PDI_a_PDI_a'_C; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 3.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF219; THIOREDOXIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00085; Thioredoxin; 2.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054282};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..552
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005573916"
FT DOMAIN 394..528
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 552 AA; 66082 MW; 273DF1800393BAF5 CRC64;
MHIDKLLIVF IFLIKLCVCH TEKGVKKEIV SINIDEFNNI LKDEGNYTLL IVYTHWSYNS
NLLLENLDKL SKLLLYEENI KLCKINAAAN TFIIDKLDVY SYPSLFMIRN KEIYRYNGVN
NIRGLLLWIY QYLDFKIYEI NNIERLDVFI DLNEYNNTIL FFIFKDLGTA NNNINNISRI
NDLINICLLT NKTLCYYIKE NNVIDYFEKN IIQDKYHYNL KNINQDSYYA ILFKNDEFDD
YFFPLNKKEL DMLSNNEYTN EEKIDHLYNW INEREQPLVI QFSEHFFSML FSNDAVTLFI
IYNNINNINK DDIIKCAKKY NHKIKFAISG TTQIFEKRLL NELLIEDNIK KPLMRITEFK
NYIRFPYKYK PQSDDQEINE KTIDDFINGY LQEKKYFYRK SERALPDEYN NGYIKIIVAD
NYDQYVYKND MNVIVLYYAP WCGHCYKFEP VYREVGKRLN LYAAKFKNYK NDIIISKIDA
VNNEIYNIHI GGPTIYLYKK GDKLNPVRYM GGRTVKNIIT GICKETQSNI DISEFLNIDL
DNEQLFENYE EL
//
