ID   A0A0L7QPC5_9HYME        Unreviewed;      1191 AA.
AC   A0A0L7QPC5;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Putative Ras GTPase-activating protein {ECO:0000313|EMBL:KOC60485.1};
GN   ORFNames=WH47_07843 {ECO:0000313|EMBL:KOC60485.1};
OS   Habropoda laboriosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Habropoda.
OX   NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC60485.1, ECO:0000313|Proteomes:UP000053825};
RN   [1] {ECO:0000313|EMBL:KOC60485.1, ECO:0000313|Proteomes:UP000053825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0110345459 {ECO:0000313|EMBL:KOC60485.1};
RA   Pan H., Kapheim K.;
RT   "The genome of Habropoda laboriosa.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ414819; KOC60485.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L7QPC5; -.
DR   STRING; 597456.A0A0L7QPC5; -.
DR   EnsemblMetazoa; XM_017939811.1; XP_017795300.1; LOC108576755.
DR   Proteomes; UP000053825; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   CDD; cd04013; C2_SynGAP_like; 1.
DR   CDD; cd05136; RasGAP_DAB2IP; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR021887; DAB2P_C.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF125; RAS GTPASE-ACTIVATING PROTEIN RASKOL; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF12004; DAB2P_C; 1.
DR   Pfam; PF00616; RasGAP; 2.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053825}.
FT   DOMAIN          1..126
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          117..235
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          293..484
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          726..754
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          947..994
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1031..1056
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1058..1085
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1191 AA;  133357 MW;  EB51B3938D134AC0 CRC64;
     MCVKPMEDNE EDKVVSMIIN YFTARNFFSK RSFRSNPLKR TKSVTKLERQ KQRGAGLRGC
     RSHESLLCGQ AVTSMDLAAV TPLHPSLLGR PHCFQVTPST GVPKYFSCRT AHERDQWLHS
     LRKSVQPDAE QTRRTDNSLQ IWLLEAKGVP AKKRYFCEVC LDSTLYARTT AKLKADLCFW
     GEHFDFHHLP SVNTIQVNLY READRKKKRD KNVLIGSVSI PVHNVTSRYL TEKWYTVVGD
     KGPLKEPPAL RVKCRFQSVD ILPVQVYQEF LEYLKTDYAS LCEKLEPVIG VKAKEDIATA
     LVAVMQREKK APQFLADLVM MDIHRIDDER LTFRGNSLAT KAMEAYLKLT GDRYLQETLG
     AVVRGAVEGG DCEVDPLKVA SVAALHKQQQ NLRNAVELAW SRILASHAHF PLELRECFRI
     FRERLADMGR EDIADNLISA SIFLRFLCPA ILSPSLFNIT HEYPNEKAAR NLTLVAKTLQ
     TLANFTRFQG KENFMEFMND LLEREAPSMK NFLQLISSPL PKDAPANNSL EFDGYIDLGK
     QLSLLHALLR ESLVTISSSS PSLPPSRLPE ILERISIALD QSGPSPVPAS HRYPNLQNNI
     FRYNDPTIAS SNTNLSVSAT STLSNHSTLN GTIRDSNEVL QSNTLGHNSS RSPNVTRAAT
     LPRNAYLPTN GKLQLQITTD DYPLEPPAFV SRSPTPIVRQ HRAIGSNRTG AGYRLTASAS
     LANVNHCQTH PTSPTRSESH SNLKDSNYNI TTSQNNQANN CTIMSQQQQQ QQQNHRHNIA
     RLQNLDIHDR EDNYNHNNYN VSRSASRNHC NKEENANQMQ HQNYNNVSKT TVNANVVVNP
     SSNLTLSINH QPNNNYNTSK TNNTTANGNL DELSDLLRYA DDEVSESKSQ KGSQISISQL
     SNVASSGYQS FAAYSQSSSP VDLSSNNANA HILSAAPLAF ANPVYHMESN HGRNGRRGSS
     SSEEREGSGG GGVEGVRGVD LSPSPPPQNN VRNMQRNNQN QWRQTNQTHR NNSEQNQSVC
     CTKLRRRLSL DSTRDLSDTS EEESCTTRRS KSRSHRSIDQ YEVEIERLQS SVDRLRARLD
     ATEDTDIDGI APDTKMKSII SRLISVEEEL RRDQQKMSAA LSYKQRVIVA QEQQIAALDA
     ANSRLMTSNT RLLSALSTLK QRYNAKSQPS SEVAALLQNI ADIGELKSSS C
//