ID A0A0L7QVH0_9HYME Unreviewed; 3913 AA.
AC A0A0L7QVH0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Dynein heavy chain 7, axonemal {ECO:0000313|EMBL:KOC62554.1};
GN ORFNames=WH47_04215 {ECO:0000313|EMBL:KOC62554.1};
OS Habropoda laboriosa.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Habropoda.
OX NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC62554.1, ECO:0000313|Proteomes:UP000053825};
RN [1] {ECO:0000313|EMBL:KOC62554.1, ECO:0000313|Proteomes:UP000053825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0110345459 {ECO:0000313|EMBL:KOC62554.1};
RA Pan H., Kapheim K.;
RT "The genome of Habropoda laboriosa.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR EMBL; KQ414727; KOC62554.1; -; Genomic_DNA.
DR STRING; 597456.A0A0L7QVH0; -.
DR Proteomes; UP000053825; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053825}.
FT DOMAIN 634..1061
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1192..1518
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1684..1821
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2045..2140
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2200..2460
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2474..2822
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 2848..3068
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3314..3426
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3463..3602
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3611..3909
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 2700..2765
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 3913 AA; 451972 MW; 55003D5759373CDE CRC64;
MAIAAHVIDL INYFFVSKTQ NECRLTRNAL EMAIMKSKIR HERKAKDFIG ECQLERPQSF
YFTKTKEFAG KLAANTLLPE WENNIRNLIS TSLQYKYTNI FESQILETKT RYEDVMQDLA
VQRVICQETC NTNFQQIPSY KLAGRTELYP KYLRNRCALR KKYYLPHRLM RNIVVKAYTS
MPQWICNFGR YRLEMDYLDF NRFLDLVEND TKKGALGIGT TYYGDIVRLI SQPRYLHDVP
PLSLPGFLNC ANNLLALQVI TRIISSIEYL LEILSDEQKM PLLKLQLKCE NNEIYFSPRM
REIYSAFHAI IDQISCVGQQ LPPLESWIGV KIQREHIKVT LPEWYLEEAH RRLADVLQNT
FEPFNDYVEK LYEKFKVVFD PETHSNITAY LSTGHSFQEC VTKVEDFNEF IREINGMPDH
EYISLGVIHQ VAAKAGLLYS TEKVRKLIIE ELVRSHRNYN LEICNTFKGI RELVANVPTT
TKELLELGEY LLMAASTLMR SLEEKITLSL RMMASLIGMT SLTKDHIELN NTTIHWLKRI
RPIFEQSSAM YEQIKFELEE KLRRKIEDLN DDVENMFPRL YIMNNMDDEN RIREYIEHMR
KFARDLDRMD ERVTWINDEE KLFQYPLSEY PRISELKEII MPYYQLIYRA YQWQRHRDVW
LDGPFEYLDS SDIENKTTEY FADFNKIRKQ YGTRIKMELA MNYPYSFQGW PDDPDPFQQP
APLKLSYQFI EDIKWFKQYI PLLTVFRNPA LRQIHWDDMS VTAGFDLTPD AGTTFRKIIK
MDLMEELEKY EMISISATKQ LMLEELLAKM INEWDGVVFT SIPYKDSGVT ILTQLDDIQA
LLEDHIVKVQ AMRGSAFVKL IEEDVKDFYF LLLRIQSTID EWIKVQVQWM YLLPIFSSKD
IVAQLPEEEV LFSQVDRIFR SSMNGVAKDP RVKETAGSVG LLEIMQEANE LMENVNDGVL
NYLEKKRLFF ARFFFLSNDD MLEILSETKD PFRVQPHLRK CFEGINKLRF DEELEICSMF
SEDNEEVRLQ EKISTAAARG CVERWLVQVE EQMVKSVRHE ILMSYLDYEV NRRVVWVRIW
PGMVVLCVAQ IYWSMEVQNS LMTHIPSTME TLHMKLRSQI LEMVQLVRGQ LSRQNRTALN
ALITLDVHAM DVVKSLIDKK IAHETDFEWL AQLRYYWQDD VFVRIIYASV AYAYEYIGNT
SRLVITPLTD RCYRTLIGAY SLHLNGAPEG PAGTGKTETT KDLSRAIAVQ CVVFNCSEGL
DYKNMGKFFK GLASCGAWSC FDEFNRIELE VLSVVAQQIL CIIQAVRGKV DTFILEGTEL
RLNPAVYVCI TMNPGYAGRS ELPDNLKVLF RTVAMMVPDY AMIGEIFLYS SGFSTARELS
TKIVTTYKLC SEQLSTQSHY DYGMRAVKTV LTAAQNIKLQ FPDENESILL LRSVIDVNLP
KFLAHDVPLF QGIVSDLFPG LELPSPSYDV LLKAVHEIAG KRNLQPVDGF LLKIIQTFEM
MIVRHGFMLV GEPFGGKTSV LHTLADALTL MNEWGDEHGA ITKYYTINPK SITSGQLYGF
FDPVSSEWTD GVCAVAFRLY CTEETPDRKW IIFDGPVDAI WIENLNTVLD DNKKLCLTSG
EVMQMSSVMS MIFEAMDLLH ASPATVSRCG MIYVEPRVLG WRPFVRSWIN ELNGEWKEGY
EENIQELFNW LVDPCLDFIR KSCHMTINAG QIHQVVSTMK LFEMFMEDAV EDNRKTFDQF
ILPWLQATML LSIVWGAAGT LDYHSRIKFN AFYLTFWKNE QSEHPLPGFL LDSLISIPGD
DLIHDCFYTY RGRGAWRRFS DLARQEEYSE TRSIVQLMIP TVDTVKYQSL FLKHIEYRRR
FLLYGETGTG KSFYIKDLIM NKLNQEKYLP TFITFTPNIT AAQTQELIVL KLYKRRRNQF
GPLPGTHCIV FIDDVNMPAK EIYGAQPPIE LLRQFFDHRI WFNLKKPETI HIYDTMFVCA
MTPPGGSRQE LYRRFLRHFN LYSISNFSED TIIRIFTSIA FIGLQRNGFT TAVMPTIMEI
VNATMNIFVN AQGELKPTPA KSHYLFNLRD FTRVITGCTM IKEDSVESKL DFTKLWVHEI
LRVFGDRLID NQDRQWLFLK VKEVVGVNLK ETFDAVFDHL PKFDEQLTHE SLQSLIFGNF
MDVDAIPSDR RYAEVKSMEE YTQVAIGCLE EYNLTHRHKM DIVLFRYALE HLARICRILV
IPCGSLLMVG VGGSGRQTLT KLASSMIGHG LFQPEIGSAY GIQEWRDDIK KVLMNSGGAD
KDFIFLLAEG QIKTESFLND IDSLLNSGEV PNLFTVEERQ EIIEMTRLAA QGGNRNLDIS
VLSILAYFVN RCREKLHIML CFSPIGDTFR IRLRLYPSLV NCCTIDWFDV WPEDALEQVA
LRSTTGVNVD EQVKINAVVA CKFFHICAKD ISVEFYNVTG RRTYVTTASF LDLIRTYAEL
MEEKQEELSL ARDRYINGLD KLEFTAAQIS QMRITLSQLR PQLEASAKET ADTMKEIETE
NIGIEKARIL VKRDEDMANV QAEVAMTLKT ECEKDLAAAL PALEDAIAAL NTLKPADITV
VRTMRSPPAG VKLVMAAVCV MMGIPAARIE DPATGKKVLD YWTPSKRLLG DMRFLETLRQ
YDKDNIPSHI IQEIKTIYMT DKNFEPKVVA RASSAAEGLC KWVRAMVLYD EVAKVVAPKK
AKLENAQSDY EKTIKFLNER RQMLAELTEK LRILNENLQV TLAKKIELET EVTNCRNKLI
RAEKLISGLG GEKNRWLTAA ANLKKSYDTL PGDILISCGM IAYLGPFSTS YRDESLEKWK
EYVEKLKIPY SEHYDFVEVL GTEVKINSWN IFGLPRDSFS IENAIIMDNS KRCSLFVDPQ
SQANKWIRNM EKQNELEIVK LTNTAYMNVI ELALEYGKPV LIENVLEDLP PALDPILTKA
IYKMGGIWYI TLGEKVIEYS LRFKLYVTTK LRNPHYLPEI FNKVTLINFA LTIGALEDQL
LGIVVAKERP DLQEKREYLI VQSAANKKAL KQVEDNILKT LSVAGASILE DEEAIEILDS
SKILSTDILK KQAAAIKTET QIEGFRQNYR PIAKHSSALY YTITDLPNID PMYQYSLTWF
INLYVISIDT ANKSKVFERR LAFLRETFTY NLYQNVCRSL FEKDKLLYSF VLYTTILMTE
KALTREEISF FLSGGVALAA VSDNPGSDWL PDKSWGEISR VHILPSFVNF QSHFTRNLNR
WKQYYDLTNP EDSPIPDPWG RSLTPFQQLI LTRMIRTDKV MIMIQRFVEV GMGLIFVVPP
PFDISKSYGD SNSLIPLIFI LSPGSDPMEA LTTFAESMNF IEKFHSISLG QGQGPIAQKL
IENAQLEGEW VCLQNCHLAA SWMPVLETTC ERFDPSNTHA NFRLWLTSYP SDHFPITILQ
NGVKMTNEPP TGLQNNILRS YKAEATKDAD FFDKEPNKKR SHSKLLYALC FFHAVVQERR
NYGAQGWNIK YGFNESDLQI SAQQLQLYIN DYEDVPFKAI VYLTGECNYG GRVTDDRDRR
CLNTILEDFY NQNVITDPNY AFADIGPEYA LPKRNEFEDY IKQIQAIPLN PPPEVLGLHM
NAGIARDLEL ANNFFQSMML IQGTMAVGST SKQDEILLNM KKDIYDRMPD LFDIEEAQKR
YPVMYMESMN TVLIQEMDRY NTLLNEIRQS LMMLEKAVNG LIVMTPALEI LAVHILSSRI
PPSWVKACAY PSLKPLPNFV NDFLDRLNFF RKWLKEDKPT TFWISGFSFV HAFLTATTQN
YARKYKIPID RIDFDYEILP AYELNKSPID GVYVYGMFLA GARWDMRSML LAESYPKILW
DSMPIIWMKP CVIDTLRAGK RYLCPLYITS ARFGVLKTTG HSTNYVLSIL IDTDYPVSHW
IKRGLALLCQ LDN
//
