ID A0A0L7R3K8_9HYME Unreviewed; 416 AA.
AC A0A0L7R3K8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Hydroxysteroid dehydrogenase-like protein 2 {ECO:0000256|ARBA:ARBA00040243};
GN ORFNames=WH47_09915 {ECO:0000313|EMBL:KOC65336.1};
OS Habropoda laboriosa.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Habropoda.
OX NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC65336.1, ECO:0000313|Proteomes:UP000053825};
RN [1] {ECO:0000313|EMBL:KOC65336.1, ECO:0000313|Proteomes:UP000053825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0110345459 {ECO:0000313|EMBL:KOC65336.1};
RA Pan H., Kapheim K.;
RT "The genome of Habropoda laboriosa.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Has apparently no steroid dehydrogenase activity.
CC {ECO:0000256|ARBA:ARBA00037788}.
CC -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; KQ414663; KOC65336.1; -; Genomic_DNA.
DR RefSeq; XP_017789981.1; XM_017934492.1.
DR AlphaFoldDB; A0A0L7R3K8; -.
DR STRING; 597456.A0A0L7R3K8; -.
DR EnsemblMetazoa; XM_017934492.1; XP_017789981.1; LOC108572293.
DR GeneID; 108572293; -.
DR OrthoDB; 4594at2759; -.
DR Proteomes; UP000053825; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd09762; HSDL2_SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR42808; HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR42808:SF3; HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF02036; SCP2; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000053825}.
FT DOMAIN 316..409
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
SQ SEQUENCE 416 AA; 45263 MW; 3EA42515562259C0 CRC64;
MINTGKLAGR TIFITGASRG IGKSIALKAA KDGANVVIAA KTADPHPKLP GTIYSAAKEI
EQMGGKALPC VVDVRDETQV VSAVENAVNK FGGIDIVINN ASAISLTGTA STDMKKYDLM
NNINTRGTFL VSKTCLPYLK KSKNPHIVNI SPPLSTNPIW FKNHVAYTMS KFGMSMCVLG
MAEEFKEDGI AVNAVWPKTA IHTAAIEMLS GPDSRNYSRK PEIMGDAVYA LICKDSKFIT
GQFLIDEEIL KNEGITDFTD YACNPANKDK LMLDFFLEEN LPELGFQNRM IPTNAQNSAP
AAQSNEKIPH IFNMIKENLN SELVNKTGAI FQFNVKGDEA GIWFVDLKNG KGSAGKGEPS
YPPDATLTMD SQNFFAMFSG KLKPASAFMM GKLKINGDLQ KAMKLEKLMH SLKSKL
//
