ID A0A0L7R4K0_9HYME Unreviewed; 218 AA.
AC A0A0L7R4K0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Vacuolar protein sorting-associated protein 37B {ECO:0000313|EMBL:KOC65810.1};
GN ORFNames=WH47_10272 {ECO:0000313|EMBL:KOC65810.1};
OS Habropoda laboriosa.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Habropoda.
OX NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC65810.1, ECO:0000313|Proteomes:UP000053825};
RN [1] {ECO:0000313|EMBL:KOC65810.1, ECO:0000313|Proteomes:UP000053825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0110345459 {ECO:0000313|EMBL:KOC65810.1};
RA Pan H., Kapheim K.;
RT "The genome of Habropoda laboriosa.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular
CC trafficking process. Required for the sorting of endocytic
CC ubiquitinated cargos into multivesicular bodies. May be involved in
CC cell growth and differentiation. {ECO:0000256|ARBA:ARBA00025010}.
CC -!- SIMILARITY: Belongs to the VPS37 family.
CC {ECO:0000256|ARBA:ARBA00007617}.
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DR EMBL; KQ414657; KOC65810.1; -; Genomic_DNA.
DR RefSeq; XP_017789662.1; XM_017934173.1.
DR AlphaFoldDB; A0A0L7R4K0; -.
DR STRING; 597456.A0A0L7R4K0; -.
DR EnsemblMetazoa; XM_017934173.1; XP_017789662.1; LOC108571997.
DR GeneID; 108571997; -.
DR OrthoDB; 2918090at2759; -.
DR Proteomes; UP000053825; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProt.
DR GO; GO:0009056; P:catabolic process; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR InterPro; IPR009851; Mod_r.
DR PANTHER; PTHR13678:SF27; LD45836P; 1.
DR PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR Pfam; PF07200; Mod_r; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR PROSITE; PS51314; VPS37_C; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053825};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 91..180
FT /note="VPS37 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51314"
SQ SEQUENCE 218 AA; 24722 MW; 993558779FA62032 CRC64;
MFKSNQEPDI PAALGLLSHQ TNDELKELLN NDEKFEDIVK DVKQFKDLET EKEVLMASNR
SLAEFNLSKQ PELQECKQIL KELSEKGNRL CTSVKEKLDE IKEKSGQMTV DTALDLLQTA
AAEIEEESET MAEKFLAGDM EVDEFFEQFL SRRKLMHLRK VKVDKLRELT RKSHFTTGSS
GYPVASNFPG LAPSIPYPTG PVSMPMPVPS GLPHYRPY
//
