ID   A0A0L8FGC3_OCTBM        Unreviewed;       886 AA.
AC   A0A0L8FGC3;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   ORFNames=OCBIM_22022313mg {ECO:0000313|EMBL:KOF62682.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF62682.1};
RN   [1] {ECO:0000313|EMBL:KOF62682.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF62682.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF62682.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ432663; KOF62682.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8FGC3; -.
DR   STRING; 37653.A0A0L8FGC3; -.
DR   EnsemblMetazoa; Ocbimv22022313m; Ocbimv22022313m.p; Ocbimv22022313m.g.
DR   EnsemblMetazoa; XM_014934609.1; XP_014790095.1; LOC106883558.
DR   OMA; KHETETH; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR000961; AGC-kinase_C.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR017892; Pkinase_C.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR22988:SF71; CITRON RHO-INTERACTING KINASE; 1.
DR   PANTHER; PTHR22988; MYOTONIC DYSTROPHY S/T KINASE-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF00433; Pkinase_C; 1.
DR   SMART; SM00133; S_TK_X; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          85..349
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          350..420
FT                   /note="AGC-kinase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51285"
FT   REGION          376..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          415..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          463..511
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          559..693
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          758..877
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        415..433
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  103153 MW;  F6EC3FF439667A8C CRC64;
     MDNESMDSIT SRIQKLEKLM QGEIQEAGIL DSLVNHQGLL DCLYVLFNEC QTQNLLKNKY
     VYEFVKKYKK TVQEIAKLRL KATDFEVKEI IGRGHFGEVR VVRERYSGTV HAMKMLEKSK
     TLAQSDVSFF SEEKEIMAKA DSCWITKLHY TFQDANYLYF VMEFYPGGDL LSLLSRYNDI
     FDEKMARFYL TEMVLAINAV HSLGYIHRDI KPENVLLDRN GHIRLADFGS AAKMSSKNLV
     SSHIPVGTPD YVAPELLKMN TASSVQRYSV EVDWWSLGVC GYEMLYGVTP FSSSDNSKSV
     TYNKIMNYQH YLKFPSSEIS KDAVDLLQHL LTEAKYRLNY QSLLVHPFFA TMNWQNIRNE
     KSPFIPSVSS LDDTSNFDEY ERLPPQPKYD DPKLRRDFSG KDLPFVGFSY FGSTKDESTD
     SSGVTSGVTS SEFDESSDDG KPSNVKLTLT VNVKEHQKIA ERCNELESNE SLLRAELEEL
     RHVVDRKELT IQRLQEDKLS LTKDLSNCAD KSNVLAKRLE QEIEAKDRVH KQGLSILNDI
     NKFNSEAEDI KCAITHAKLD ELKQVIKVLE GQNSAMVKQL FNKDRTLIEC QKHLLSTQEQ
     LEKAKDRLEK ERKKSMDEQR WENTRIRNLE DSWRHQMQIK DDEIKRLQGR IDDLNHQNAK
     TSKCHICHDG KLLNKAEKLT EDMSKKYEDE NKLRIHLEKK LDEQLKKQMT NDKWLSDSTE
     SLKDELAENQ KTIAHQDKLI KELLEKADNQ EMTWKRISED LELKIKVLED ESNKLRTKEK
     SNAELKLSLL QQVNTYQEEV KQLRNQLQAV TDKITREEES VTLELENKIE ELRKQLEKQS
     NEKELSYERE KQHLRKIKEL ENILDDKENL KANNEQRLLT KIKVSV
//