ID   A0A0L8FH46_OCTBM        Unreviewed;       541 AA.
AC   A0A0L8FH46;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE            EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN   ORFNames=OCBIM_22021066mg {ECO:0000313|EMBL:KOF62962.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF62962.1};
RN   [1] {ECO:0000313|EMBL:KOF62962.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF62962.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF62962.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class 1 subfamily. {ECO:0000256|ARBA:ARBA00009701}.
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DR   EMBL; KQ431974; KOF62962.1; -; Genomic_DNA.
DR   RefSeq; XP_014789897.1; XM_014934411.1.
DR   AlphaFoldDB; A0A0L8FH46; -.
DR   STRING; 37653.A0A0L8FH46; -.
DR   EnsemblMetazoa; Ocbimv22021066m; Ocbimv22021066m.p; Ocbimv22021066m.g.
DR   EnsemblMetazoa; XM_014934411.1; XP_014789897.1; LOC106883419.
DR   GeneID; 106883419; -.
DR   KEGG; obi:106883419; -.
DR   OMA; QRECELM; -.
DR   OrthoDB; 2911650at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR46047; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F; 1.
DR   PANTHER; PTHR46047:SF3; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        517..535
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..291
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          203..282
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          319..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          483..510
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        374..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  61554 MW;  6C4CC122B6CA36D1 CRC64;
     MSTSVERQFK EHDQNGLWNG VFKKLKKAED LSVIDSRLTT LEARKPENRN KNRYRDVNPY
     DHSRIILDVN NGCGDYINAN LIEISKANRR YILTQGPLEN TVGQFWQMVW EQNTMGIVML
     NRIMEKGTVK CHQYWPPGSK HGYDEDLTFS DSGFKVVLLK EEENEHYIVR SLKLWNLNTD
     ESRNVLHFQY TTWPDFGVPS SPHTFLNFLM AVRESGYLNN NVGPCIVHCS AGIGRSGTFC
     LVDSALVIVE KDWNMEVIDV ESMLQDMRYY RMGLVQTPDQ LRFSFLSIID GGKQILSNPP
     PIKENEIDTH TKRFFFKRNC EMPPMPPKRT TSLMPGDEFG NDLISENADS KNTSSFLTTN
     GDLAQSLSAT DHLTSNHLSS SVPSQKSQSD TTTTSTTTIS TTTTTTTNPT VYKEKGHPNE
     SEPQQNNITA QLSSSSSSPQ APLSHNGQTV EYLLSVGSST DPVNVATTGE SDVDGYEYRR
     KIREERKRNT QKLIEDMKRK QRECELMRQR NRYLTPLYIG IVLALGGSLL LYRYYNNGNQ
     Q
//