ID A0A0L8FIU8_OCTBM Unreviewed; 1059 AA.
AC A0A0L8FIU8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Protein artemis {ECO:0000256|ARBA:ARBA00039759};
DE AltName: Full=DNA cross-link repair 1C protein {ECO:0000256|ARBA:ARBA00042677};
GN ORFNames=OCBIM_22018470mg {ECO:0000313|EMBL:KOF63750.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF63750.1};
RN [1] {ECO:0000313|EMBL:KOF63750.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF63750.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF63750.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
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DR EMBL; KQ430702; KOF63750.1; -; Genomic_DNA.
DR RefSeq; XP_014789471.1; XM_014933985.1.
DR AlphaFoldDB; A0A0L8FIU8; -.
DR STRING; 37653.A0A0L8FIU8; -.
DR EnsemblMetazoa; Ocbimv22018470m; Ocbimv22018470m.p; Ocbimv22018470m.g.
DR EnsemblMetazoa; XM_014933985.1; XP_014789471.1; LOC106883094.
DR GeneID; 106883094; -.
DR KEGG; obi:106883094; -.
DR OrthoDB; 23465at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF38; PROTEIN ARTEMIS; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 264..339
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT REGION 388..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 924..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..613
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1002
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1059 AA; 119440 MW; 2CFBAE74963E1442 CRC64;
MSTFEGRMLE YTFISLDRFD RKNLSSTMFF LSHTHFDHTQ GLGEPEFLKV LEKRQSTYLY
CSKLVQTILL KMSCFKKLEP HIKVLEVNSP TVIEVPNDEH SSQSTCSTIT VTLLQAGHCL
GSVMFLIEGS EGTVLYTGDF RWEENEFFRM PWLKSGDNMK LIKSLYVDTT FCIPEAFHVP
TRTQSYEAIL SEVTKHFKKD DNNYVCIFSK TGFGYEHLLE KLAKAFRMKV HVDDFKKSVY
DTIPKLKDSF TTSARSTRIH FHNTQYCPQL RTKISELLVI KVSVMWFVEG SRRKGCVDAL
QWVGQNTCRV CYSFHPSFEE VQALVRYLKP ENVLPNVCPQ CYTLEQTQIK LNKILDESKP
KKQQQHCSSN DSQLGMMKLK KVPEISYPPR TSVSFGDSES SYNQESQISI SESTSSNENE
NMSSSCDVQG VESDSVMLQS HGTPRDISEE STSHYTKLRD KFKDKISQHS NTYREMSSDM
TSQSNNSKQV MSNNKLSQQY NSHEETLESV TSHHCNSQSH SLENMSQNSI PCEFMLPTMA
AEQIRDISPK HVTELTHMSP KPVSSNQGNM SPKYTESNKD MLTMKSPRDK EDKEKLLSDA
PLEQSEEEKY KTPEGNGNYV NYHQMSPNNI YTKNYTEQNE VKKITSQNQS KVLDQKEATD
NQRDTKIYKD QLVNLSQIFR PLYYFGGNSS QTDPGSIQHI MKKSFDSKDS SKNIPETKLN
VDDKSSDCIS DGKSKAIALQ DGPLSNNSHS SSFDHSVCKI TEKSKRMSET SPSKNKSEIQ
SSASSGVTKS FSLAMNKEVT SMFSVDEDNN TINESLKSET SCSIPEVSAG GNNTGNICCM
SKEIPSDKTV SQSIPASSQL GKRKHETIAS CDDNCSNHKN VCDVQLVNNV ESFISHSTVL
ENCTVEEKPV NQNSLKSKHR INLDSTTSAQ STSINTSQSN SNGEVLCKSR EDNQPIEKSL
SQTTIVISDS QNSEWDPDCE NKNLSESQET MPPSPFSISS SSESLLSPKT LERMSSLHNN
CDNNNLPVNC HDNVTSPHNS SSQDEVIIIE KKIPRFVID
//
