ID A0A0L8FLP1_OCTBM Unreviewed; 478 AA.
AC A0A0L8FLP1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=OCBIM_22015876mg {ECO:0000313|EMBL:KOF65320.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF65320.1};
RN [1] {ECO:0000313|EMBL:KOF65320.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF65320.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF65320.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR EMBL; KQ429601; KOF65320.1; -; Genomic_DNA.
DR RefSeq; XP_014788933.1; XM_014933447.1.
DR AlphaFoldDB; A0A0L8FLP1; -.
DR STRING; 37653.A0A0L8FLP1; -.
DR EnsemblMetazoa; Ocbimv22015876m; Ocbimv22015876m.p; Ocbimv22015876m.g.
DR EnsemblMetazoa; XM_014933447.1; XP_014788933.1; LOC106882686.
DR OMA; RPEHSMQ; -.
DR OrthoDB; 3060590at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24082:SF283; NUCLEAR HORMONE RECEPTOR HR96; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 78..153
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 241..471
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 54660 MW; 7B66110E06D9AFDA CRC64;
MTTRTDTLKP NGTSEVGTTC KQSPDIMEES SNSMPMSDQS MLLQWSDDSC EPDSSTSTQT
KGNIKEQKRR PKPKDGTKLI CRVCNDVALG YNFDAVTCES CKAFFRRNAL KKKVFNCTFD
GNCRLDPHTR KFCSSCRLKK CFAVGMKKDW ILNEEQLAKR RQRLTSSQQN NTPLNNNNNN
SSPSPSASSI SSFEYMQPLY EDAEPALDVP NLKTWVYPAD KYPVSHHLFW NTLEVSESIS
QTITYIRMVV QEHENTFNEN YPSGAFVIPK NTKEFFVLSN VFICRLINFM KYIPDFQKLP
KEDRISIFRG SIREVSLIRA SMAYSYIENM WVFKDCNGDK SYLDTNILKA TLGDCLYSKL
AQFIRSFKIA TNDDKVIMIL LLLIEFFDQD KSSLLSSEVV VAAQEKYTSW LKTYIDCKYN
DEIGKVLFPR VLVKLMDVRE IGEICNEATQ NFLLQGIDPL TAEVLDLKLM VDKIGNSP
//
