ID A0A0L8FYJ0_OCTBM Unreviewed; 301 AA.
AC A0A0L8FYJ0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Regucalcin {ECO:0000256|ARBA:ARBA00016808};
DE EC=3.1.1.17 {ECO:0000256|ARBA:ARBA00013227};
DE AltName: Full=Gluconolactonase {ECO:0000256|ARBA:ARBA00032464};
GN ORFNames=OCBIM_22004180mg {ECO:0000313|EMBL:KOF69738.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF69738.1};
RN [1] {ECO:0000313|EMBL:KOF69738.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF69738.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF69738.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glucono-1,5-lactone + H2O = D-gluconate + H(+);
CC Xref=Rhea:RHEA:10440, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16217, ChEBI:CHEBI:18391; EC=3.1.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00001589};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SMP-30/CGR1 family.
CC {ECO:0000256|ARBA:ARBA00008853}.
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DR EMBL; KQ425220; KOF69738.1; -; Genomic_DNA.
DR RefSeq; XP_014785794.1; XM_014930308.1.
DR RefSeq; XP_014785796.1; XM_014930310.1.
DR AlphaFoldDB; A0A0L8FYJ0; -.
DR STRING; 37653.A0A0L8FYJ0; -.
DR EnsemblMetazoa; Ocbimv22004180m; Ocbimv22004180m.p; Ocbimv22004180m.g.
DR EnsemblMetazoa; XM_014930308.1; XP_014785794.1; LOC106880394.
DR EnsemblMetazoa; XM_014930310.1; XP_014785796.1; LOC106880394.
DR GeneID; 106880394; -.
DR KEGG; obi:106880394; -.
DR OMA; AEGCYWS; -.
DR OrthoDB; 2955046at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR GO; GO:0004341; F:gluconolactonase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR008367; Regucalcin.
DR InterPro; IPR013658; SGL.
DR InterPro; IPR005511; SMP-30.
DR PANTHER; PTHR10907; REGUCALCIN; 1.
DR PANTHER; PTHR10907:SF47; REGUCALCIN; 1.
DR Pfam; PF08450; SGL; 1.
DR PRINTS; PR01791; REGUCALCIN.
DR PRINTS; PR01790; SMP30FAMILY.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 15..264
FT /note="SMP-30/Gluconolactonase/LRE-like region"
FT /evidence="ECO:0000259|Pfam:PF08450"
SQ SEQUENCE 301 AA; 33758 MW; 0DCFF620EA90DF06 CRC64;
MSVSVALKNV CQKSGEGPHW EESTKSLLFV DVETGHLHKW NSVDYTHTKF KADGYVSFII
PRESGGYIVA CFAQLADFDW ETQELKPFIK IESDKPENVF NDGKCDSYGR LWTGTMKTIK
DKLEITEAGH LYRIDKDLSV NAIKDKINIS NGMTWTADDK TMFYTHTLPR KVFSYDYDVS
TGEISREQVV IDFEGQELHE YGVPDGMTID LNDKIWLACF SSGKVFQIDP ETGKILTSVK
FPVSQVTSCC FGGPNYDELY VTSSASRLTE NQLQNEEKLA GSVFKVTELG AKGKAAPVFQ
G
//
