ID A0A0L8G2Z3_OCTBM Unreviewed; 1508 AA.
AC A0A0L8G2Z3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Fibrillin-2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=OCBIM_22001914mg {ECO:0000313|EMBL:KOF70950.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF70950.1};
RN [1] {ECO:0000313|EMBL:KOF70950.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF70950.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF70950.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KQ424474; KOF70950.1; -; Genomic_DNA.
DR STRING; 37653.A0A0L8G2Z3; -.
DR EnsemblMetazoa; Ocbimv22001914m; Ocbimv22001914m.p; Ocbimv22001914m.g.
DR OMA; CIDMRRE; -.
DR GO; GO:0031012; C:extracellular matrix; IEA:UniProt.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 10.
DR Gene3D; 2.10.25.10; Laminin; 27.
DR Gene3D; 3.90.290.10; TGF-beta binding (TB) domain; 6.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR017878; TB_dom.
DR InterPro; IPR036773; TB_dom_sf.
DR PANTHER; PTHR24050:SF20; -; 1.
DR PANTHER; PTHR24050; PA14 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 23.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF00683; TB; 6.
DR SMART; SM00181; EGF; 27.
DR SMART; SM00179; EGF_CA; 27.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 7.
DR SUPFAM; SSF57581; TB module/8-cys domain; 6.
DR PROSITE; PS00010; ASX_HYDROXYL; 24.
DR PROSITE; PS01186; EGF_2; 16.
DR PROSITE; PS50026; EGF_3; 21.
DR PROSITE; PS01187; EGF_CA; 9.
DR PROSITE; PS51364; TB; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 46..100
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 112..149
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 154..195
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 243..287
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 304..345
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 350..406
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 395..436
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 437..478
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 479..521
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 522..563
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 647..683
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 689..729
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 730..768
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 771..808
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 813..854
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 855..895
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 900..953
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 952..994
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 995..1036
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1037..1078
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1079..1120
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1125..1177
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 1192..1233
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1234..1273
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1274..1314
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1355..1395
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1400..1453
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF70950.1"
SQ SEQUENCE 1508 AA; 165108 MW; 99A77EFF982DCC26 CRC64;
VNECVNNPNL CTNGECINTQ GSYKCECYRG YILQPDGKTC RDTRRGLCYT QVHRGQCSNP
SYSPMTKSTC CCTEDNANNG WGTPCEICPK PNDREYKTIC PHGPGKDGNG GGINECAMYP
DACQNGACED LDMGYRCICD SGYKMDDTGR ACVDINECAE DKYICDGGKC RNSPGSYTCM
CPTGFIQSKT TKMCEDINEC ESFDTLCVGG NCVNLAGSFR CECTVPGTVL DSSARVCIDN
RRGTCWKKIH NDLCEDNIKG DTLRSECCGT LGKAWGSPCE RCPSQSSRNC PKGYAIISGV
KCTDINECDV LPGICQNGYC INTDGSYKCN CPEGLSIDQS GHRCVDYRKS SCYLEYNHGR
CSGELFGQFH QAICCCSVGT AWGSPCNSCP QPDSDINECL EIPDICSNGV CHNTPGGFNC
DCKQGFAIDG RGFNCTDIDE CRISFGVCAN GTCVNTPGAF TCDCNEGYEG VMMNQMCIDV
DECARRQPAP CRGGTCVNTA GAFECLCPAG HELSPDKTTC NDVDECSTDS AICSNGICTN
YMGGYQCSCF NGYEPNPQKT SCTDINECKV NQGGCSSLCV NTPGSWNCGC KMGFMLMPDL
KSCQDVDECR EREDICAGGK CTNLNGGYNC ICTDGLRPSE DNKNCIDINE CEDPNICRTG
TCVNTHGSFT CKCNVGYSMQ KGIGNGCFDT DECETGENTC DRNANCINTE GSYKCDCKVG
YREVGGKCRD KNECVRNNGG CHPDADCINQ VGSFRCVCED GFSGDGFTCT DVDECSLNPY
LCEHGQCFNY EGGYKCECDM GFTPTDNDRA CIDIDECVMF ENLCVNGKCQ NGVGLFNCIC
NQGYQVDPTG GNCTDIDECR IPDNCLYGNC KNLEGGYECH CPFNYELNPS GTGCIDMRKG
NCYSTYYKST TWPHELICEN ELSGNLTKMM CCCSVAKAWN TPCEACPERH TNENECERRR
SPCVGNANCL NTKGSYECRC PVGYKLAPNK RRCRDMDECR QLIGICQNGR CLNTFGSFTC
NCQTGYRLSQ DFRNCLDIDE CAETPYVCHH GRCNNIEGSF ECSCFNGYKL SDTGDECIDI
DECFTESNIC YNGNCINTDG SYICNCPSGY VLSSDKRKCI DMRVGICYRT FANGQCLNPT
PMNMTRKECC CSKSVAWGDT ICSVCPTQNT KAFKLLCPYI GHIEDPNGNR KDINECMMYP
DYCTNGRCIN TDGSYRCECN TGFQVDDTKT RCIDINECLT GRICGRGTCT NLIGQFECSC
EDGYAPGPEG TCEDLNECQT ELNKCAFRCV NTPGSFRCIC PIGYRLADDN RHCVDVDECL
IDTNKCPYNC KNLVGSFLCV CPEGYRAIGQ DVCIDINECR EGNPCENGRC RNINGGYICS
CYPGYEPSPD KKKCLDLREG YCYNQLVHGR CVPSREIKRT ARHICCCTGL AAAWGPSCER
CPAIGSNQFA RICPNEIGYL PNGTDIDECA SGQHNCPYGC INTISSYKCG CPKGLKEGPN
GDCVGKKQ
//
