ID A0A0L8G414_OCTBM Unreviewed; 235 AA.
AC A0A0L8G414;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=isopentenyl-diphosphate Delta-isomerase {ECO:0000256|ARBA:ARBA00012057};
DE EC=5.3.3.2 {ECO:0000256|ARBA:ARBA00012057};
GN ORFNames=OCBIM_22000555mg {ECO:0000313|EMBL:KOF71767.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF71767.1};
RN [1] {ECO:0000313|EMBL:KOF71767.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF71767.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF71767.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the 1,3-allylic rearrangement of the homoallylic
CC substrate isopentenyl (IPP) to its highly electrophilic allylic isomer,
CC dimethylallyl diphosphate (DMAPP). {ECO:0000256|ARBA:ARBA00003951}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=isopentenyl diphosphate = dimethylallyl diphosphate;
CC Xref=Rhea:RHEA:23284, ChEBI:CHEBI:57623, ChEBI:CHEBI:128769;
CC EC=5.3.3.2; Evidence={ECO:0000256|ARBA:ARBA00000374};
CC -!- PATHWAY: Isoprenoid biosynthesis; dimethylallyl diphosphate
CC biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate:
CC step 1/1. {ECO:0000256|ARBA:ARBA00004826}.
CC -!- SIMILARITY: Belongs to the IPP isomerase type 1 family.
CC {ECO:0000256|ARBA:ARBA00007579}.
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DR EMBL; KQ423995; KOF71767.1; -; Genomic_DNA.
DR RefSeq; XP_014784278.1; XM_014928792.1.
DR RefSeq; XP_014784279.1; XM_014928793.1.
DR AlphaFoldDB; A0A0L8G414; -.
DR EnsemblMetazoa; Ocbimv22000556m; Ocbimv22000556m.p; Ocbimv22000555m.g.
DR EnsemblMetazoa; XM_014928792.1; XP_014784278.1; LOC106879292.
DR EnsemblMetazoa; XM_014928793.1; XP_014784279.1; LOC106879292.
DR GeneID; 106879292; -.
DR OrthoDB; 777305at2759; -.
DR UniPathway; UPA00059; UER00104.
DR GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02885; IPP_Isomerase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR011876; IsopentenylPP_isomerase_typ1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR NCBIfam; TIGR02150; IPP_isom_1; 1.
DR PANTHER; PTHR10885; ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE; 1.
DR PANTHER; PTHR10885:SF0; ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PIRSF; PIRSF018427; Isopntndiph_ism; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229}.
FT DOMAIN 51..204
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 235 AA; 27388 MW; 19B4A65F3D0E82BD CRC64;
MHSASEVLVN LDPTQAKLMS EECILVDEMD RVLDKATKQE CHLMANINKG MLHRAFSVFL
FNSNGELLLQ QRSSKKITYP NHITNTCCSH PLFKEAELEE NDAIGVRRAA QRKLQHELGI
PPEQVPLEDI HYITRMHYKA GNVPLDGKWG EHEIDYVLFI KKNVDLNLNP NEVKSTMYLN
CDGVKDLMKN FRDRGILLTP WFQLIVDNFL FQWWDNLQCL NTQYDHKTIY RLSKT
//
