ID A0A0L8G858_OCTBM Unreviewed; 330 AA.
AC A0A0L8G858;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
DE Flags: Fragment;
GN ORFNames=OCBIM_22038444mg {ECO:0000313|EMBL:KOF73069.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF73069.1};
RN [1] {ECO:0000313|EMBL:KOF73069.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF73069.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF73069.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; KQ423341; KOF73069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8G858; -.
DR EnsemblMetazoa; Ocbimv22038444m; Ocbimv22038444m.p; Ocbimv22038444m.g.
DR EnsemblMetazoa; XM_014927823.1; XP_014783309.1; LOC106878578.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 2.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT DOMAIN 264..309
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF73069.1"
SQ SEQUENCE 330 AA; 35780 MW; D2C03B2ACB6C40D8 CRC64;
AGSIFFLNAT RGTGKTFVTQ LILAKILHEK QIALAIASSG IAATLLPGGR TAHSAFKLPL
DLVSAEVLTC NISKNAEEAE VLRQCHLISL KGIRDSTASM GGVTLLLSGD ILQTLPVIPK
GSRSDEVLAC LKSSTLWPQV KTLSLSTNMR AHLLGDSMSA AFAEDILALG EGKVPRNDMG
DISMSELCNT MDNPSNLLET VFPNLESNNA DINWLSERTI LAPQNVAVSA INDQLISPIP
SEERIYKSID WTSDPQDIVS YSNEVLNSLE PAGLPHHILR LRVGCPIMLI RNLLLHKQCN
GTRLVIKSLM PHLTEATIVT ECRRSENVFI
//
