ID A0A0L8GEE2_OCTBM Unreviewed; 865 AA.
AC A0A0L8GEE2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=CUB domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=OCBIM_22034976mg {ECO:0000313|EMBL:KOF75298.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF75298.1};
RN [1] {ECO:0000313|EMBL:KOF75298.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF75298.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF75298.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KQ422233; KOF75298.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8GEE2; -.
DR STRING; 37653.A0A0L8GEE2; -.
DR EnsemblMetazoa; Ocbimv22034976m; Ocbimv22034976m.p; Ocbimv22034976m.g.
DR OMA; CFFERAC; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046:SF5; EPHRIN_REC_LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR Pfam; PF14670; FXa_inhibition; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 236..274
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 717..785
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 240..250
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 865
FT /evidence="ECO:0000313|EMBL:KOF75298.1"
SQ SEQUENCE 865 AA; 97406 MW; 358975E45310A243 CRC64;
MDDLKLYGKD EAQVSSLVDT VYNFSADIRM EFGLRKCSVL VLKRGKIKCM DGLTIPSGEV
IKQIEETGYK YLGILEMDKL MEKEMTGKFK VEYLRRLRLI LKSKLNERNK IEAINTWAVS
LRYGAWVIAW AVDEQNSLDR KTRKLLTRYG SLHPKTSCKV NKGGCQKQCI DTKTGPKCTC
PSGYKLHTDK KSCLDIDECA DGGGGCSDNC VNTHGSYECT CPKGFKTLSD LKTCTDIDEC
SIPSTCDHIC INTPGSFHCK CRPGFENYGI THCADVNECT NNIGGCEQGC ENTEGSFKCK
CKEGYRLHPN QKDCMRADVC IRLKTPAKAQ LLCQSVGDTN MCILRCNSNA HFTSDASRTD
YTFICNKETK YEWSHNNKTY VVLPSCSDAV LPPGFKRKAV FLMMTAEKCR LKKHTTDNFK
ENLLQTLHKK KRYKCTKLCH VQNVSLQCGT KRRRFRQTLS KQKTYITAEF EIEVAPKAPT
ESCNINCTRK KTERRLKKTI KRLRRSINKE KFSVIFENIQ YGVRKRSFKA ARTLMTCRKG
NILVNQECIS CSIGTYHDVE KGICVPCSHG KYQDMEGQTE CKNCPNQAEG KGVLGAKNIS
DCAGLCSRGY FADDGLEPCQ PCPIGTYQTD IGRTKCIPCG RSIKTRGVAS TSFQDCIVKT
ICGPGHFYDV ESESCKDCPI GFYQSESSQN FCIPCPGDTT TDGGNSKNSS DCKNRKCGGY
IGLLRGRLES PNYPGDYPNN VNCTWFIKPG KGRRILIIIP EIFLRAEDKC GDQLVMRKSN
QKNTGAGFSI PYVTYNEEYQ DLMEDIVTDG QLYKPYQHQQ LFKCQRLRVG LEPTFLADTT
AVLLLSQSKL SNFFIHKGDN PFYLK
//
