ID A0A0L8GJW6_OCTBM Unreviewed; 297 AA.
AC A0A0L8GJW6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Transmembrane protein 120A {ECO:0008006|Google:ProtNLM};
GN ORFNames=OCBIM_22032258mg {ECO:0000313|EMBL:KOF77302.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF77302.1};
RN [1] {ECO:0000313|EMBL:KOF77302.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF77302.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF77302.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM120 family.
CC {ECO:0000256|ARBA:ARBA00009700}.
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DR EMBL; KQ421506; KOF77302.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8GJW6; -.
DR EnsemblMetazoa; Ocbimv22032259m; Ocbimv22032259m.p; Ocbimv22032258m.g.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR012926; TACAN/TMEM120B.
DR PANTHER; PTHR21433:SF0; TRANSMEMBRANE PROTEIN 120 HOMOLOG; 1.
DR PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR Pfam; PF07851; TMPIT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 28..65
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 35257 MW; D84E51E239DA2845 CRC64;
MDEQLVCHRR ADDADDEESK PSPQDPVIKN CLEDWNDLEE EYVELESLHR TYQKKLNEMV
SLQDKCLKQI AHHRYRMKTI QESLKRNTKD LSAEDKSEMK SLQQKLLDRK EAFRELEECL
PHQNGLYLSV ILGQVNVSLL NKGDKFQYKR EYERFKLVVS YIIMCLSFVQ TFFGSYRWVD
AVLHFLLVWY YCTLTIRESI LVVNGSRIKG WWLTHHFIST VCAGISLIWP DGWSYQVFRT
RYVIFIMYLS FVYVMQYYYQ NGCLYRLRTL GKRHGMDITV GKLSPLFFLS LSLGCVP
//
