ID A0A0L8GLH3_OCTBM Unreviewed; 538 AA.
AC A0A0L8GLH3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Recombining binding protein suppressor of hairless {ECO:0008006|Google:ProtNLM};
GN ORFNames=OCBIM_22031643mg {ECO:0000313|EMBL:KOF77827.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF77827.1};
RN [1] {ECO:0000313|EMBL:KOF77827.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF77827.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF77827.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Su(H) family.
CC {ECO:0000256|ARBA:ARBA00009704}.
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DR EMBL; KQ421305; KOF77827.1; -; Genomic_DNA.
DR RefSeq; XP_014779925.1; XM_014924439.1.
DR RefSeq; XP_014779926.1; XM_014924440.1.
DR AlphaFoldDB; A0A0L8GLH3; -.
DR EnsemblMetazoa; Ocbimv22031648m; Ocbimv22031648m.p; Ocbimv22031643m.g.
DR EnsemblMetazoa; XM_014924439.1; XP_014779925.1; LOC106876047.
DR EnsemblMetazoa; XM_014924440.1; XP_014779926.1; LOC106876047.
DR GeneID; 106876047; -.
DR OrthoDB; 1384914at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd01176; IPT_RBP-Jkappa; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR InterPro; IPR036358; BTD_sf.
DR InterPro; IPR040159; CLS_fam.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR InterPro; IPR038007; RBP-Jkappa_IPT.
DR PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR Pfam; PF09270; BTD; 1.
DR Pfam; PF09271; LAG1-DNAbind; 1.
DR Pfam; PF20144; TIG_SUH; 1.
DR SMART; SM01268; BTD; 1.
DR SMART; SM01267; LAG1_DNAbind; 1.
DR SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 105..236
FT /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT /evidence="ECO:0000259|SMART:SM01267"
FT DOMAIN 237..386
FT /note="Beta-trefoil DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01268"
SQ SEQUENCE 538 AA; 60390 MW; 6FAA546A1D918AF7 CRC64;
MPAGSLTPPD KISGDSISMA NIRPLGISTL TNTIKTPPSP MPTPSPPINR ITGDIDHSDS
RITHPFSRSH WTTDVLENRH VGQYQDQRLT REAMRKYLRD RGDQVLVILH AKVAQKSYGN
EKRFFCPPPC IYLFNNGWKR KKEQLERDGA TEQESLVCAF MGIGNSDQDM VQLNLEGKNY
CAAKTLYISD SDKRKHFMLS VKMFYGNSQD IGMFNSKRIK VISKPSKKKQ SLKNADLCIA
SGTKVALFNR LRSQTVSTRY LHVEDGNFHA SSTQWGAFTI HLLDDNESES EEFTVRDGYI
HYGSTIKLVC SVTGMALPRL IIRKVDKQTA LLDADDPVSQ LHKCAFYMKD TERMYLCLSQ
ERIIQFQATP CPKEPNKEMI NDGASWTIIS TDKAEYTFFE GMGPVKATVT PVPVVSSLHL
NGGGDVAMLE LTGENFTPIL KVWFGDVEAE TMYRCEESML CVVPDISAFR AGWRWVRQPL
QVPVTLVRND GIIYATGLTF TYTPEPGPRQ HCNAVDRVLR ANSDPPPPSS VNYSAPPM
//
