ID   A0A0L8GMH4_OCTBM        Unreviewed;      1125 AA.
AC   A0A0L8GMH4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=SLED domain-containing protein {ECO:0000259|Pfam:PF12140};
DE   Flags: Fragment;
GN   ORFNames=OCBIM_22031075mg {ECO:0000313|EMBL:KOF78246.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF78246.1};
RN   [1] {ECO:0000313|EMBL:KOF78246.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF78246.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF78246.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ421153; KOF78246.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8GMH4; -.
DR   STRING; 37653.A0A0L8GMH4; -.
DR   EnsemblMetazoa; Ocbimv22031075m; Ocbimv22031075m.p; Ocbimv22031075m.g.
DR   OMA; HWSLKNG; -.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd20093; MBT_SFMBT_rpt1; 1.
DR   CDD; cd20094; MBT_SFMBT_rpt2; 1.
DR   CDD; cd20095; MBT_SFMBT_rpt3; 1.
DR   CDD; cd20096; MBT_SFMBT_rpt4; 1.
DR   Gene3D; 2.30.30.140; -; 4.
DR   Gene3D; 3.90.1150.190; SLED domain; 1.
DR   InterPro; IPR004092; Mbt.
DR   InterPro; IPR021987; SLED.
DR   InterPro; IPR038348; SLED_sf.
DR   PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR   PANTHER; PTHR12247:SF129; SAM DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02820; MBT; 4.
DR   Pfam; PF12140; SLED; 1.
DR   SMART; SM00561; MBT; 4.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR   PROSITE; PS51079; MBT; 4.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          271..371
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          379..481
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          491..599
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          606..706
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   DOMAIN          752..866
FT                   /note="SLED"
FT                   /evidence="ECO:0000259|Pfam:PF12140"
FT   REGION          133..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          892..996
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1014..1034
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1100..1119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..227
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        940..964
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        965..996
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1017..1034
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1125
FT                   /evidence="ECO:0000313|EMBL:KOF78246.1"
SQ   SEQUENCE   1125 AA;  127303 MW;  4C9EED1C33762D1C CRC64;
     MKEQFSAALI NHTTQMKPTF PAGIPANMHC TPVTTLGAFT TTQVLSPVYL PANFPGFSQP
     VFTNNQLFVS TPPTVVLQPN FQCLQSIPTA SLTNTFPAVN AIEPVSTTNV EAADEPVLLE
     EEDPNEELVI TNSKEQNYEQ NQEETEVGSS VCEEGKDEVS VDLDSDASCE ICPDTDNKSV
     DSVILTEKYD QFVSSESPVS ENVEEEEEEE DEEEEEEEDE EDYTEEISSQ NPSEVPVSPS
     GSEEIPDPHC NLDMCEDTED GLLETYEEPD FVWEEYLQET GALEVPPTAF KHVECSLQSG
     FVKGMKLEVA VKSTPDTYWV ASVIMTCGPL LRLRYDGYGD DGSADFWHDL TASEIHSIGW
     CAQNNKTLMP PDELKNKIGN WRDFLTTSLV GAATAPLYLL DKTTGTTPVD QIKQGMRLEL
     QDHINPNHVW IVKVLENVGG RLYLRQEGLN HSETDFWLFY LNHLLHPIDW AKQNNYEYSP
     PKEYEDQYTK EEWDEIFQEA LKEAEAMPLP VDIFKDQIEI RRHNFKAGWK LEAVNPVTKN
     EICPATVIDV IDDKYFIVEI DDVRPLNERS YIRFGCHIDS PGIFPAMWCR RKGIHLKKPA
     GWDGEFDWAE YLSNIDCKAA PRNCFGSVCM DVPYHQFQRG LKLEAVNPDN SNQICAATIT
     KIVDRLMWIH LDNSSKMKAS FIEDIDSHNL FPVGWCESNG YQLNPPRRTG FRRPHKQVAV
     VQPEPVTIES HLSATDTYNK IKNVNIEEDT WCPKIYYNHR CFSGPYLAKS RIAELPKSIG
     PGPIKLVMTE VLTMLINVAY KSSRVLRELQ VDGEDNPNMH QQVLKAKYKG KSYRAAVELC
     RNVKQLDEFC RQICIKLECC PNLISPHCID DDCPENCSQL TKTKYTYYYG KKKRKIGRPP
     GGHSNLENGP RKTGKRRKKR KGSLSRKSRS SMDDIYADDV TAENSNTVSE KRSASPSSEN
     NSSKSDTKKT SDSKPAIKRK YTHHVPPRSE IHTRGAKLPK YSFERKTHKK ILITPAPPSS
     SAKSLPSPTT EAALPITPIS PKEEISIKKE EENDDMCVDI LSNPLYWTVS DVVSFIKSTD
     CAQFARLFRQ ELDGTPVHRS FTQETGRKSE RKLGRKSTTG LTIVW
//