ID   A0A0L8GPM3_OCTBM        Unreviewed;       874 AA.
AC   A0A0L8GPM3;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=HAP1 N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OCBIM_22030059mg {ECO:0000313|EMBL:KOF78996.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF78996.1};
RN   [1] {ECO:0000313|EMBL:KOF78996.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF78996.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF78996.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC   -!- SIMILARITY: Belongs to the milton family.
CC       {ECO:0000256|ARBA:ARBA00007007}.
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DR   EMBL; KQ420886; KOF78996.1; -; Genomic_DNA.
DR   RefSeq; XP_014779132.1; XM_014923646.1.
DR   AlphaFoldDB; A0A0L8GPM3; -.
DR   EnsemblMetazoa; Ocbimv22030075m; Ocbimv22030075m.p; Ocbimv22030059m.g.
DR   EnsemblMetazoa; XM_014923646.1; XP_014779132.1; LOC106875482.
DR   GeneID; 106875482; -.
DR   OrthoDB; 2909788at2759; -.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006933; HAP1_N.
DR   InterPro; IPR022154; TRAK1/2_C.
DR   PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR   PANTHER; PTHR15751:SF12; TRAFFICKING KINESIN-BINDING PROTEIN MILT; 1.
DR   Pfam; PF04849; HAP1_N; 1.
DR   Pfam; PF12448; Milton; 1.
DR   SMART; SM01424; HAP1_N; 1.
DR   SMART; SM01423; Milton; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128}.
FT   DOMAIN          1..275
FT                   /note="HAP1 N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01424"
FT   DOMAIN          343..508
FT                   /note="Trafficking kinesin-binding protein C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01423"
FT   REGION          97..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          433..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          612..640
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          678..742
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          801..853
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          132..205
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          234..275
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        433..450
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        451..475
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        612..626
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        679..707
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..728
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   874 AA;  96130 MW;  33894490EEF9C80E CRC64;
     METFDEDLDP FALAMREHIR EEDEAVEHIL AIVENKERDL ELAARIGQTL LEKNKELSDK
     ADHLEDQLSA ANDKVSQLKH DLSMKDELLR FYTQDLENAE SESDSSTPTQ QQPSSSGADS
     RVKSFNLSSI NVDNLKKKVR LLEDDNLQLR LETSQLASVT EDYEEKEEKL VQDCLKQLAD
     VNSQLEVFSD ELARKTEESS RQKEEITSLL SQVVDLQRKN REVSVENLDY SKKLEAFKDT
     QHKLAKELSE WQDRYDELLE LFEEVQDELR TLRRKHKPSA SKHYMSTSSL MRGDSLASEL
     ESSMRGEIEY PAGYSPAERR IHNWKIFETA RAAKKASQRM KDKRSSSLFL KAAGGDSSTP
     GSASVSVRSS LYLSDGESFI SDGYNADLDS MSGWPPFRAY SSNSTNIGRP GVPGSNDLET
     ALRRLLVKRP WDINDKDGKS SSDSSKENEK TQISLDPTFS DGFSTPMLSG TPESMLSSGV
     SALSATGSAG LHFKIPEKLQ IVKPMEGSVT LKHWQQLAQP HMTGIFESRP GVQIKGERKL
     DLEEEVYNLS DYEEDDDYQL CHSKRFAESS TIYTYTDSMV MHPSDQVYLD EKQSDNNSSI
     KRLWDLERKK AKDRKLLQKP KHGNKDMGEP PAACSRKSTR KTADTTTCSM SLGLAAILNE
     RGLCDTWKFG LRCKGNSVSP GGDGTSSDDS HSGIYTRSGG SSSDATPTHF YRKKKSSSEV
     KETKDDGNAN SSSVDALDSS SEVGAKTQSA GASFLSTLKS KGFSIYGILS SSSSASTENN
     NSVGEAITTD SSIDSTLKCT TATDGAASPT STATTTTTTT NNTTIINDNN NSSRDSNRSN
     NNSSPSATTA NDIALGKSGG VLGAITSLRQ GGIL
//