ID A0A0L8GX75_OCTBM Unreviewed; 656 AA.
AC A0A0L8GX75;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350, ECO:0000256|PIRNR:PIRNR038922};
GN ORFNames=OCBIM_22026307mg {ECO:0000313|EMBL:KOF81626.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF81626.1};
RN [1] {ECO:0000313|EMBL:KOF81626.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF81626.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF81626.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC ribonucleoprotein complex that mediates the cotranslational targeting
CC of secretory and membrane proteins to the endoplasmic reticulum (ER).
CC {ECO:0000256|PIRNR:PIRNR038922}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR038922}. Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}.
CC -!- SIMILARITY: Belongs to the SRP72 family.
CC {ECO:0000256|ARBA:ARBA00007676, ECO:0000256|PIRNR:PIRNR038922}.
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DR EMBL; KQ420023; KOF81626.1; -; Genomic_DNA.
DR RefSeq; XP_014777253.1; XM_014921767.1.
DR AlphaFoldDB; A0A0L8GX75; -.
DR STRING; 37653.A0A0L8GX75; -.
DR EnsemblMetazoa; Ocbimv22026307m; Ocbimv22026307m.p; Ocbimv22026307m.g.
DR EnsemblMetazoa; XM_014921767.1; XP_014777253.1; LOC106874148.
DR GeneID; 106874148; -.
DR KEGG; obi:106874148; -.
DR OMA; NDMKVLA; -.
DR OrthoDB; 91080at2759; -.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-UniRule.
DR GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR InterPro; IPR026270; SRP72.
DR InterPro; IPR031545; SRP72_TPR-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR Pfam; PF08492; SRP72; 1.
DR Pfam; PF17004; SRP_TPR_like; 1.
DR Pfam; PF13181; TPR_8; 1.
DR PIRSF; PIRSF038922; SRP72; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038922};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR038922};
KW Signal recognition particle {ECO:0000256|ARBA:ARBA00023135,
KW ECO:0000256|PIRNR:PIRNR038922};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 217..250
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 531..580
FT /note="Signal recognition particle SRP72 subunit RNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF08492"
FT REGION 526..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 74438 MW; 72C13369753DB151 CRC64;
MTSLTQLYSD LNKLKQSQDY ERGIKVANKI IHEHNGETLA FHCKMVCLIN LGRFDEVMIA
MKKYPSLSND LKFEKAYCEY RLNRTNEALR TLREVANPCL RTQELLAQVL YRLEQYDECY
TLYKQLIKNS EDEFDEERQT NLAAVLSSLQ MWNKKQVDDP GLKDLSYELC YNKACLMIGQ
NKFKDAEEKL QKAEVVCRKS FEDDPESTEE DINEEVAVLR TQLAYVLQKQ GRPEEALQIY
NQVLKTKPSD IGVTAVASNN IVTLNKEQNV FDSKKKIKAA TSGSVNQKLM SMQQRKIKMN
QGLLYMYTNQ SDQVRNVVKE LQDKFSDASS AVLIEVAQHV RDKHVPKAIE VLKNYIAKDS
VDERIKLILS QLYLSQGSVF QACDVLKSIE TLRYKPAVVG VLVSLYVSQE DVQSASKTLG
DAVTWHKQNM PNSPELMVLM KANAKFQMKH GDPQQAASLL EEISKKNPKD SHILAQLFSA
YSLFDSKKAE QISHQLPSVD EIISGVDVDE LEKSFSSMAP KYLKRIQKTE PSPSSDGVLL
IKTKKKKKKK KAKMPKNYDA CVTPDPERWL PRRERSYYRG KRKDKTKNIS KGTQGATSPA
GDIDASKQTS GSEASSPRPA ANVTKPSPQP ANRHQQQQHS SSGRSTNNKK KKKGKR
//
