ID A0A0L8HB39_OCTBM Unreviewed; 339 AA.
AC A0A0L8HB39;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
DE Flags: Fragment;
GN ORFNames=OCBIM_22018688mg {ECO:0000313|EMBL:KOF86397.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF86397.1};
RN [1] {ECO:0000313|EMBL:KOF86397.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF86397.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF86397.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; KQ418653; KOF86397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8HB39; -.
DR STRING; 37653.A0A0L8HB39; -.
DR EnsemblMetazoa; Ocbimv22018688m; Ocbimv22018688m.p; Ocbimv22018688m.g.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 2.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT DOMAIN 251..296
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF86397.1"
FT NON_TER 339
FT /evidence="ECO:0000313|EMBL:KOF86397.1"
SQ SEQUENCE 339 AA; 37163 MW; 42F3AEB1C219F51D CRC64;
CCRKTSGRHF FLDAPGGTGK SFVTRLILAK IRREKQIALA VASSRIAATL LPGGRMAHSA
FKLPLDLGAL EALDRSLKDI RDSTASMGGV TLLLSGDFRQ TLPVIPKGTR ADEVRACLKS
SMLWLQVKML SLSTNMRAHL LGDSTSAAFA EDILALGEGK VPKNDKGDIA ISELCNTVDN
PSELLETVFP NLESNYADIN WLSERTILAP KNVAVSAIND QLIGRIPGEE RIYKSIDRTS
DSQDIVNYPI EFLNSLEPAG LPPHILRLRV GCPIILIRNL LPPKLCNGTR FVVKSLVPHL
IEATIVTECG RGENVFISRM HLYPSGSDIP FHFRRSQFP
//
