ID   A0A0L8HE96_OCTBM        Unreviewed;      1089 AA.
AC   A0A0L8HE96;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Myotubularin phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=OCBIM_22016710mg {ECO:0000313|EMBL:KOF87512.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF87512.1};
RN   [1] {ECO:0000313|EMBL:KOF87512.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF87512.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF87512.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR   EMBL; KQ418387; KOF87512.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8HE96; -.
DR   EnsemblMetazoa; Ocbimv22016708m; Ocbimv22016708m.p; Ocbimv22016710m.g.
DR   CDD; cd13208; PH-GRAM_MTMR5_MTMR13; 1.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR   InterPro; IPR030564; Myotubularin_fam.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR022096; SBF1/SBF2.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR   PANTHER; PTHR10807:SF109; SET DOMAIN BINDING FACTOR, ISOFORM A; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   Pfam; PF06602; Myotub-related; 1.
DR   Pfam; PF12335; SBF2; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00568; GRAM; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50211; DENN; 1.
DR   PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE   3: Inferred from homology;
FT   DOMAIN          1..77
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   DOMAIN          822..1089
FT                   /note="Myotubularin phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51339"
FT   REGION          354..386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          701..721
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          742..801
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          985..1023
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1045..1089
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        756..773
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        787..801
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        991..1023
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1089
FT                   /evidence="ECO:0000313|EMBL:KOF87512.1"
SQ   SEQUENCE   1089 AA;  122702 MW;  6E1E9336B5C9C4D4 CRC64;
     MDKEIRAVFI RLFAELFTGY RSCLTLIRIH PEPFITFHKA YFLGQRAMVD DEFACRVLDC
     MSFSTFVAER GPPYRVCDIF DEVYATMQDQ LKEERSSTND EKMMAHIKEI AQQLYLNENP
     NSQPYVPKFP KPTEGAYSRI HQMPFPKLDG SIILNIIQEG VAKHNLNNKL LNVRPHQPRI
     VPMGPPISSV VDKQKVVDNN ARRLEVLRNC INFIFENKIS DARKIFPAVL RALNNKVARL
     ALTQELSYHI QSNRAMLEHQ QFDLVVRLLN CALQNDSSMD ENGVAYAILP LATSFCRKLC
     TGVIQFAYTC VQEHAVWRNN QFWEASFYLD VQKEIRQLYL PHYEEHFVAE NTREEAKNSS
     YGRDSSLDPS RSKSCTPDTH RRSAPSLFRP KEIGALDIAA EQLRIWPNLS KEQQEEMVNN
     EESTVYSQAI HYANRMVYMM IPLDVNRRDK NTVGFDEKCA SNSNITASLA ESDSLDAESG
     FDESEASDVG ANAIRFVTRF VDKVCSESSV TQEHLKSLHQ MIPGVVAMHI ETLESIHRES
     KRLPPIQKPK ILEPTILPGE EIVMEGLRVY LLPDGREEGV GGSLGGPCLL PAEGAIFLTT
     YRIIFKGIPC DPLACEQIVV RCFPVSTLTR EKRISVQYLQ HLDQWLHEGL QLRSNIFQLM
     KIVFDEEVSS DDVETLRKLL HKMRNPARVF DTFTFNQHPY SSTLQPTPLH KSKEKSSTLK
     AEVMENSSVD FRQLAKKTLM KTVRRAGLKP KQSSRKQKYM LPTPPTSRRT LSPRSSDSES
     ERPSSEIYDE LSSTNYSDGS PSVIDEAEYS MQWSADAKSL EKLMERPGYQ DYVRLGIGSL
     PNSGSRTRND QFRITDVNSN YSVCRSYPAL LIVPHSVTDE SIRKFSRCYR QSRFPIITWR
     HSRTKALLLR GSGFHSRSLM GMLRHHNTVT GTSSGETSSS IEQENYFRSL VAVTPNSMRS
     YQSSYSDSLT SLDSLMMVGS NEITIPETPE PLRKSTFNRT AGLSNTRASG GAKSKTLDIS
     SPASQLTSSQ TVIAAGNIAS SATLSASPSS QSAETKLSSV SSSGTAQRKS MITRASSTIL
     TPTINGTPC
//